Evidence map›Paper›PMID 28600435›Full record

ArticleThe Journal of cell biology2017

RASSF4 controls SOCE and ER-PM junctions through regulation of PI(4,5)P

Yu-Ju Chen, Chi-Lun Chang, Wan-Ru Lee, Jen Liou

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 67 citations in OpenAlex.

  1. PIP4K attenuates PIP5K lipid kinase activity by disrupting membrane-mediated dimerization.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Dual Role ofBiology · 2025
    Review
  7. Review
  8. Article
  9. Imaging interorganelle contacts at a glance.Journal of cell science · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Roles of Cholesterol and PtdIns(4,5)PAdvances in experimental medicine and biology · 2023
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yu-Ju ChenDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX.
Chi-Lun ChangDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX.ORCID 0000-0003-0017-2243
Wan-Ru LeeDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX.ORCID 0000-0003-2689-5458
Jen LiouDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX jen.liou@utsouthwestern.edu.ORCID 0000-0003-1546-3115
The University of Texas Southwestern Medical Center · US

Funding

Functions and regulation of endoplasmic reticulum-plasma membrane junctionsR01GM113079 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI LIOU, JEN · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM113079
6 · The paper itself

Abstract

RAS association domain family 4 (RASSF4) is involved in tumorigenesis and regulation of the Hippo pathway. In this study, we identify new functional roles of RASSF4. First, we discovered that RASSF4 regulates store-operated Ca

Indexed as

Calcium SignalingADP-Ribosylation Factor 6ADP-Ribosylation FactorsCell MembraneEndoplasmic ReticulumFemaleHeLa CellsHumansMicroscopy, FluorescenceMicroscopy, VideoNeoplasm ProteinsORAI1 ProteinPhosphatidylinositol 4,5-DiphosphatePhosphotransferases (Alcohol Group Acceptor)Protein TransportRNA Interference1-phosphatidylinositol-4-phosphate 5-kinaseADP-Ribosylation Factor 6ADP-Ribosylation FactorsARF6 protein, humanNeoplasm ProteinsORAI1 ProteinORAI1 protein, humanPhosphatidylinositol 4,5-DiphosphatePhosphotransferases (Alcohol Group Acceptor)RASSF4 protein, humanSTIM1 protein, humanStromal Interaction Molecule 1Synaptotagmin IISynaptotagminsSYT2 protein, humanSYT3 protein, humanTumor Suppressor Proteins

Identifiers

PMID28600435
PMCPMC5496610
OpenAlexW2623986179

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.