ArticleVirology journal2017
Zika vector transmission risk in temperate Australia: a vector competence study.
Article in Virology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Secondary vectors of Zika Virus, a systematic review of laboratory vector competence studies.PLoS neglected tropical diseases · 2023Pooled it
- Pooled it
- Zika virus: An updated review of competent or naturally infected mosquitoes.PLoS neglected tropical diseases · 2017Pooled it
- Advances in viral encephalitis: Viral transmission, host immunity, and experimental animal models.Zoological research · 2023Review
- The interplay between vector microbial community and pathogen transmission on the invasive Asian tiger mosquito,Frontiers in microbiology · 2023Review
- Developing Wolbachia-based disease interventions for an extreme environment.PLoS pathogens · 2023Article
- A wMel Wolbachia variant in Aedes aegypti from field-collected Drosophila melanogaster with increased phenotypic stability under heat stress.Environmental microbiology · 2022Article
- Uncovering the Worldwide Diversity and Evolution of the Virome of the MosquitoesMicroorganisms · 2021Article
- Zika Virus Potential Vectors amongPathogens (Basel, Switzerland) · 2021Article
- Warming temperatures could expose more than 1.3 billion new people to Zika virus risk by 2050.Global change biology · 2021Article
- Uncovering the genetic diversity within theVirus evolution · 2021Article
- Review
- Contrasted transmission efficiency of Zika virus strains by mosquito species Aedes aegypti, Aedes albopictus and Culex quinquefasciatus from Reunion Island.Parasites & vectors · 2020Article
- Estimation of mosquito-borne and sexual transmission of Zika virus in Australia: Risks to blood transfusion safety.PLoS neglected tropical diseases · 2020Article
- Vector competence of Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus mosquitoes for Mayaro virus.PLoS neglected tropical diseases · 2020Article
- One-step RT-qPCR assay for ZIKV RNA detection in Aedes aegypti samples: a protocol to study infection and gene expression during ZIKV infection.Parasites & vectors · 2020Article
- Different populations of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) from Central Africa are susceptible to Zika virus infection.PLoS neglected tropical diseases · 2020Article
- Broad dengue neutralization in mosquitoes expressing an engineered antibody.PLoS pathogens · 2020Article
- Vector competence ofRevista panamericana de salud publica = Pan American journal of public health · 2020Review
- Vector Competence: What Has Zika Virus Taught Us?Viruses · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundZika virus is an emerging pathogen of global importance. It has been responsible for recent outbreaks in the Americas and in the Pacific region. This study assessed five different mosquito species from the temperate climatic zone in Australia and included Aedes albopictus as a potentially invasive species.
methodsMosquitoes were orally challenged by membrane feeding with Zika virus strain of Cambodia 2010 origin, belonging to the Asian clade. Virus infection and dissemination were assessed by quantitative PCR on midgut and carcass after dissection. Transmission was assessed by determination of cytopathogenic effect of saliva (CPE) on Vero cells, followed by determination of 50% tissue culture infectious dose (TCID
resultsCulex mosquitoes were found unable to present Zika virus in saliva, as demonstrated by molecular as well as virological methods. Aedes aegypti, was used as a positive control for Zika infection and showed a high level of virus infection, dissemination and transmission. Local Aedes species, Ae. notoscriptus and, to a lesser degree, Ae. camptorhynchus were found to expel virus in their saliva and contained viral nucleic acid within the midgut. Molecular assessment identified low or no dissemination for these species, possibly due to low virus loads. Ae. albopictus from Torres Strait islands origin was shown as an efficient vector. Cx quinquefasciatus was shown to harbour Wolbachia endosymbionts at high prevalence, whilst no Wolbachia was found in Cx annulirostris. The Australian Ae. albopictus population was shown to harbour Wolbachia at high frequency.
conclusionsThe risk of local Aedes species triggering large Zika epidemics in the southern parts of Australia is low. The potentially invasive Ae. albopictus showed high prevalence of virus in the saliva and constitutes a potential threat if this mosquito species becomes established in mainland Australia. Complete risk analysis of Zika transmission in the temperate zone would require an assessment of the impact of temperature on Zika virus replication within local and invasive mosquito species.
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