ArticleThe Journal of the Acoustical Society of America2017
Regular chondrocyte spacing is a potential cause for coherent ultrasound backscatter in human articular cartilage.
Article in The Journal of the Acoustical Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- A deep neural network-enhanced multi-scale coupled model of patient-specific acoustic wave propagation for mechanotransduction stimulation of healthy and osteoarthritic knee articular cartilage.Biomechanics and modeling in mechanobiology · 2026Article
- Realistic Ultrasound Simulations of Healthy and Osteoarthritic Cartilage.Journal of imaging · 2026Article
- The osteochondral regeneration paradox: why biomimetic scaffolds are biologically superior but injectable systems dominate the clinic.RSC advances · 2026Review
- Ultrasound grayscale histogram analysis for early rheumatoid arthritis cartilage assessment.Advances in rheumatology (London, England) · 2025Article
- Advanced Topics in Quantitative Acoustic Microscopy.Advances in experimental medicine and biology · 2023Article
- Quantitative Ultrasound Assessment of Early Osteoarthritis in Human Articular Cartilage Using a High-Frequency Linear Array Transducer.Ultrasound in medicine & biology · 2022Article
- [Shaoyangzhugu Formula regulates p19Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The potential of quantitative ultrasound (QUS) to assess the regular cellular spacing in the superficial cartilage zones was investigated experimentally and numerically. Nine osteochondral samples, extracted from two human cadaver knee joints, were measured using a 50-MHz ultrasound scanning device and evaluated using Mankin score. Simulated backscattered power spectra from models with an idealized cell alignment exhibited a pronounced frequency peak. From the peak, cell spacing in the range between 15 and 40 μm between cell layers was detected with an average error of 0.2 μm. The mean QUS-based cell spacing was 28.3 ± 5.3 μm. Strong correlation (R
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Registered trials
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