Evidence map›Paper›PMID 28599497›Full record

ArticleOncology letters2017

Monoclonal antibodies against autocrine motility factor suppress gastric cancer.

Hahn-Sun Jung, Su In Lee, Seung-Hoon Kang, Jin Sang Wang, Eun Hee Yang, Byungwook Jeon, Jayhyuk Myung, Ji Young Baek, Song-Kyu Park

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  4. Metastasis prevention: targeting causes and roots.Clinical & experimental metastasis · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hahn-Sun JungBoryung Central Research Institute, Boryung Pharmaceutical Co. Ltd., Ansan-Si, Kyeongki-Do 03127, Republic of Korea.
Su In LeeCollege of Pharmacy, Republic of Korea University, Sejong 30019, Republic of Korea.
Seung-Hoon KangBoryung Central Research Institute, Boryung Pharmaceutical Co. Ltd., Ansan-Si, Kyeongki-Do 03127, Republic of Korea.
Jin Sang WangBoryung Central Research Institute, Boryung Pharmaceutical Co. Ltd., Ansan-Si, Kyeongki-Do 03127, Republic of Korea.
Eun Hee YangBoryung Central Research Institute, Boryung Pharmaceutical Co. Ltd., Ansan-Si, Kyeongki-Do 03127, Republic of Korea.
Byungwook JeonBoryung Central Research Institute, Boryung Pharmaceutical Co. Ltd., Ansan-Si, Kyeongki-Do 03127, Republic of Korea.
Jayhyuk MyungBoryung Central Research Institute, Boryung Pharmaceutical Co. Ltd., Ansan-Si, Kyeongki-Do 03127, Republic of Korea.
Ji Young BaekCollege of Pharmacy, Republic of Korea University, Sejong 30019, Republic of Korea.
Song-Kyu ParkCollege of Pharmacy, Republic of Korea University, Sejong 30019, Republic of Korea.
Boryung Pharma (South Korea) · KRKorea University · KRKorea University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autocrine motility factor (AMF), which is a secreted form of phosphoglucose isomerase, is mainly secreted by various tumors and has cytokine-like activity. AMF is known to stimulate proliferation, survival and metastasis of cancer cells, and angiogenesis within a tumor. The present study investigated whether inhibition of AMF using targeted-antibodies was able to suppress the growth of cancer. A migration assay using a Boyden chamber was utilized to measure the activity of AMF on the motility of cancer cells. A recombinant human AMF (rhAMF) prepared from

Indexed as

A549anticancer activityautocrine motility factormonoclonal antibodyNCI-N87

Identifiers

PMID28599497
PMCPMC5453026
OpenAlexW2607226492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.