ArticleOncology letters2017
Colorectal cancer in cases of multiple primary cancers: Clinical features of 59 cases and point mutation analyses.
Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Clinico-Morphological and Genetic Features of Colorectal Cancer in Multiple Primary Cancers Cases.Biochemical genetics · 2026Article
- Plasma Methylated SEPT9 as a Novel Biomarker for Predicting Liver Metastasis in Colorectal Cancer.Molecular biotechnology · 2024Article
- Synchronous Colorectal and Prostate Cancer: Dual PET/CT Approach for Detecting and Distinguishing Metastatic Patterns.Nuclear medicine and molecular imaging · 2023Article
- Developing prognostic nomograms to predict overall survival and cancer-specific survival in synchronous multiple primary colorectal cancer based on the SEER database.Journal of cancer research and clinical oncology · 2023Article
- Genetic characteristics of a patient with multiple primary cancers: A case report.World journal of clinical cases · 2021Article
- Retrospective study of prognosis of patients with multiple colorectal carcinomas: synchronous versus metachronous makes the difference.International journal of colorectal disease · 2021Article
- The Rare Diagnosis of Synchronous Breast and Colonic Cancers: A Case Report and Review of Literature.Cureus · 2021Article
- Clinicopathologic features and prognosis of synchronous and metachronous multiple primary colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021Article
- Targeted sequencing identifies the mutational signature of double primary and metastatic malignancies: a case report.Diagnostic pathology · 2019Article
- Clinical value of preoperative methylated septin 9 in Chinese colorectal cancer patients.World journal of gastroenterology · 2019Article
- A Rare Occurrence of Three Primary Malignancies of the Rectum, Breast, and Kidney in the Same Patient: A Case Report and Review of the Literature.Case reports in surgery · 2019Article
- Molecular biological analysis in a patient with multiple lung adenocarcinomas.Thoracic cancer · 2018Article
- Synchronous prostate and rectal cancer, a case report.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyArticle
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aimed to investigate the occurrence and clinical features of cases of multiple primary cancers including colorectal cancer (MPCC). The medical records of patients with colorectal cancer (CRC) who underwent surgery at the Third Xiangya Hospital of Central South University (Changsha, China) between August 2007 and August 2014 were retrospectively analyzed. Patients with MPCCs were identified and mutation analyses were performed on colon specimens. The results revealed that among 1,311 patients with CRC, 59 had MPCC (including 35 cases of ≥1 CRC with ≥1 other cancer type, and 24 cases with multiple CRCs and no other primary cancers). Foci occurred on the right side of the colon (n=32), in the rectum (n=28), and on the left side of the colon (n=24). MPCCs were synchronous in 24 patients, metachronous in 32 patients, and both in 3 patients. Age of onset and presence of polyps were identified as significantly different between MPCC and CRC overall (P<0.05); however, sex or adenoma incidence were not observed to differ significantly between groups. Mutation incidence rates in 26 specimens were 11.54% for KRAS proto-oncogene GTPase (
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