Evidence map›Paper›PMID 28599406›Full record

ArticleOncology letters2017

Ocoxin oral solution

Iera Hernandez-Unzueta, Aitor Benedicto, Elvira Olaso, Eduardo Sanz, Cristina Viera, Beatriz Arteta, Joana Márquez

4 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03541772 phase2completednot on this map

"Combined Oncoxin-Viusid® Treatment With Radiotherapy and Chemotherapy in Patients With Head and Neck Cancer. Phase II, Randomized and Double-blind Study"

TypeinterventionalSponsorCatalysis SLRan2015 to 2017Enrolled60ConditionsHead Cancer NeckArmsOncoxin-Viusid®, Placebo
NCT03549494 phase2completednot on this mapstarted 2018, after this paper: background citation

Effect of Ocoxin®-Viusid® Nutritional Supplement on the Quality of Life of Patients With Advanced Stomach Cancer and Esophagogastric Junction. Phase II Clinical Trial.

TypeinterventionalSponsorCatalysis SLRan2018 to 2023Enrolled45ConditionsStomach Neoplasm, Gastrointestinal Neoplasms, Digestive System Neoplasm, Esophageal NeoplasmsArmsOcoxin-Viusid®
NCT03559543 phase2completednot on this mapstarted 2018, after this paper: background citation

Evaluation of the Effect of the Ocoxin®-Viusid® Nutritional Supplement on the Quality of Life of Patients With Metastatic Colorectal Adenocarcinoma. Phase II

TypeinterventionalSponsorCatalysis SLRan2018 to 2024Enrolled40ConditionsColorectal Neoplasm, Intestinal Neoplasms, Gastrointestinal Neoplasms, Digestive System NeoplasmArmsOcoxin-Viusid
NCT06363201 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Exploratory Study to Evaluate the Effect and Safety of the Use of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours

TypeinterventionalSponsorCatalysis SLRan2024 to 2025Enrolled40ConditionsAdvanced Cancer, Advanced Solid Tumor, Lymphoma, Hodgkin, Central Nervous System TumorArmsOcoxin Oral solution
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Ocoxin as a complement to first line treatments in cancer.International journal of medical sciences · 2021
    Review
  8. Oncoxin-ViusidMolecular and clinical oncology · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Iera Hernandez-UnzuetaDepartment Cell Biology and Histology, School of Medicine and Dentistry, Basque Country University, Leioa, E-48940 Bizkaia, Spain.
Aitor BenedictoDepartment Cell Biology and Histology, School of Medicine and Dentistry, Basque Country University, Leioa, E-48940 Bizkaia, Spain.
Elvira OlasoDepartment Cell Biology and Histology, School of Medicine and Dentistry, Basque Country University, Leioa, E-48940 Bizkaia, Spain.
Eduardo SanzCatalysis S.L, Toledo, E-28016 Madrid, Spain.
Cristina VieraDepartment Cell Biology and Histology, School of Medicine and Dentistry, Basque Country University, Leioa, E-48940 Bizkaia, Spain.
Beatriz ArtetaDepartment Cell Biology and Histology, School of Medicine and Dentistry, Basque Country University, Leioa, E-48940 Bizkaia, Spain.
Joana MárquezDepartment Cell Biology and Histology, School of Medicine and Dentistry, Basque Country University, Leioa, E-48940 Bizkaia, Spain.
University of the Basque Country · ESInstituto de Catálisis y Petroleoquímica · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is an aggressive disease in which patients usually die due to its metastatic progression to the liver. Up to date, irinotecan is one of the most used chemotherapeutic agents to treat CRC metastasis with demonstrated efficacy. However, the severity of the side effects constitute the main limitation to its use in the treatment. Consequently, new complementary therapies are being developed to avoid these adverse effects while maintaining the efficacy of the antitumoral drugs. Ocoxin oral solution (OOS

Indexed as

colorectal cancerlivermetastasisnutrient mixtureocoxin oral solution

Identifiers

PMID28599406
PMCPMC5453048
OpenAlexW2607412152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.