Evidence map›Paper›PMID 28599268›Full record

ArticleEnvironmental health perspectives2017

Drinking Water Salinity and Raised Blood Pressure: Evidence from a Cohort Study in Coastal Bangladesh.

Pauline FD Scheelbeek, Muhammad A H Chowdhury, Andy Haines, Dewan S Alam, Mohammad A Hoque, Adrian P Butler, Aneire E Khan, Sontosh K Mojumder, Marta A G Blangiardo, Paul Elliott and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 102 citations in OpenAlex.

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  18. Extreme climatic events and human biology and health: A primer and opportunities for future research.American journal of human biology : the official journal of the Human Biology Council · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Pauline FD Scheelbeek *Department of Population Health, London School of Hygiene & Tropical Medicine, London, UK
Muhammad A H ChowdhuryInitiative for Non-communicable Diseases, Health Systems and Population Studies, icddr,b, Dhaka, Bangladesh
Andy HainesDepartment of Population Health, London School of Hygiene & Tropical Medicine, London, UK
Dewan S AlamFaculty of Health, York University, Toronto, Ontario, Canada
Mohammad A HoqueSchool of Earth and Environmental Sciences, Faculty of Science, University of Portsmouth, Portsmouth, UK
Adrian P ButlerDepartment of Civil and Environmental Engineering, Imperial College London, London, UK
Aneire E KhanInternational Centre for Diarhoeal Disease Research (icddr,b), Dhaka, Bangladesh
Sontosh K MojumderDacope Upazilla Health Complex, Khulna, Bangladesh
Marta A G BlangiardoMRC-PHE Centre for Environment and Health, London, UK
Paul ElliottMRC-PHE Centre for Environment and Health, London, UK
Paolo VineisMRC-PHE Centre for Environment and Health, London, UK
MRC Centre for Environment and HealthInternational Centre for Diarrhoeal Disease Research · BDLondon School of Hygiene & Tropical Medicine · GBImperial College London · GBUniversity of Portsmouth · GBYork University · CA

Funding

Medical Research Council MR/L01341X/1Wellcome Trust
6 · The paper itself

Abstract

backgroundMillions of coastal inhabitants in Southeast Asia have been experiencing increasing sodium concentrations in their drinking-water sources, likely partially due to climate change. High (dietary) sodium intake has convincingly been proven to increase risk of hypertension; it remains unknown, however, whether consumption of sodium in drinking water could have similar effects on health.

objectivesWe present the results of a cohort study in which we assessed the effects of drinking-water sodium (DWS) on blood pressure (BP) in coastal populations in Bangladesh.

methodsDWS, BP, and information on personal, lifestyle, and environmental factors were collected from 581 participants. We used generalized linear latent and mixed methods to model the effects of DWS on BP and assessed the associations between changes in DWS and BP when participants experienced changing sodium levels in water, switched from "conventional" ponds or tube wells to alternatives [managed aquifer recharge (MAR) and rainwater harvesting] that aimed to reduce sodium levels, or experienced a combination of these changes.

resultsDWS concentrations were highly associated with BP after adjustments for confounding factors. Furthermore, for each 100 mg/L reduction in sodium in drinking water, systolic/diastolic BP was lower on average by 0.95/0.57 mmHg, and odds of hypertension were lower by 14%. However, MAR did not consistently lower sodium levels.

conclusionsDWS is an important source of daily sodium intake in salinity-affected areas and is a risk factor for hypertension. Considering the likely increasing trend in coastal salinity, prompt action is required. Because MAR showed variable effects, alternative technologies for providing reliable, safe, low-sodium fresh water should be developed alongside improvements in MAR and evaluated in "real-life" salinity-affected settings. https://doi.org/10.1289/EHP659.

Indexed as

SalinityWater SupplyAdultBangladeshBlood PressureClimate ChangeCohort StudiesDrinking WaterFemaleGroundwaterHumansHypertensionMiddle AgedSodiumDrinking WaterSodium

Identifiers

PMID28599268
PMCPMC5730519
OpenAlexW2622612835

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.