ArticleJournal of X-ray science and technology2017
Collimated superfine x-ray beam based x-ray luminescence computed tomography.
Article in Journal of X-ray science and technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Automated Restarting Fast Proximal Gradient Descent Method for Single-View Cone-Beam X-ray Luminescence Computed Tomography Based on Depth Compensation.Bioengineering (Basel, Switzerland) · 2024Article
- Oxygenation imaging in deep tissue with X-Ray luminescence computed tomography (XLCT).Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
- Contrast agents for x-ray luminescence computed tomography.Applied optics · 2021Article
- Focused x-ray luminescence imaging system for small animals based on a rotary gantry.Journal of biomedical optics · 2021Article
- Radiation dose estimation for pencil beam X-ray luminescence computed tomography imaging.Journal of X-ray science and technology · 2021Article
- X-ray luminescence imaging for small animals.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- High-resolution x-ray luminescence computed tomography.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- Method for improving the spatial resolution of narrow x-ray beam-based x-ray luminescence computed tomography imaging.Journal of biomedical optics · 2019Article
- Focused x-ray luminescence computed tomography: experimental studies.Proceedings of SPIE--the International Society for Optical Engineering · 2019Article
- Background luminescence in x-ray luminescence computed tomography (XLCT) imaging.Applied optics · 2019Article
- Time domain X-ray luminescence computed tomography: numerical simulations.Biomedical optics express · 2019Article
- X-ray luminescence computed tomography using a focused x-ray beam.Journal of biomedical optics · 2017Article
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Authors and funding
4 authors.
Funding
Abstract
X-ray luminescence computed tomography (XLCT) is a hybrid imaging modality with the potential to achieve a spatial resolution up to several hundred micrometers for targets embedded in turbid media with a depth larger than several millimeters. In this paper, we report a high spatial resolution XLCT imaging system with a collimated superfine x-ray beam in imaging the deeply embedded targets. A collimator with a 100 micrometer pinhole was mounted in the front of a powerful x-ray tube to generate a superfine x-ray pencil beam with a beam diameter of 0.175 mm. For the phantom experiment of four capillary targets with an edge-to-edge distance of 400 micrometers, we were able to reconstruct the targets in a depth of 5 mm successfully, which were validated with microCT images. We have further investigated the effect of different x-ray beam diameters on the reconstructed XLCT images with numerical simulations. Our results indicate that XLCT has the ability to image successfully multiple deeply embedded targets when the collimated x-ray beam diameter is less than or equal to the target edge-to-edge distance. Our numerical simulations also demonstrate that XLCT can achieve a spatial resolution of 200 micrometers for targets embedded at a depth of 5 mm if the scanning beam has a diameter of 100 micrometers.
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