ReviewOrganogenesis2017
The epidemiology of supernumerary teeth and the associated molecular mechanism.
Review in Organogenesis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.
- Minimally invasive intraoral removal of mesiodens via a transnasal, non-endoscopic approach: a systematic review on the purpose of 10 cases.Oral and maxillofacial surgery · 2024Pooled it
- Sfrp4 Is Required for Proper Dental Formation and Stem Cell Regulation.Journal of dental research · 2026Article
- Minimally invasive surgical extraction of an impacted supernumerary tooth in right maxilla with use of a 3D-printed surgical guide and mixed reality: a case description.Quantitative imaging in medicine and surgery · 2026Article
- Craniofacial size in individuals with supernumerary teeth: A multicenter geometric morphometric study.BMC oral health · 2026Article
- Involving supernumerary teeth in "qpdb" teeth numbering system.Scientific reports · 2026Article
- Proposed differential diagnosis and classification of non-syndromic and syndromic supernumerary teeth.BMC oral health · 2026Article
- CBCT-Assisted Clinic and Radiographic Diagnosis of an Atypically Erupted Odontoma Associated With Supernumerary Tooth.Case reports in dentistry · 2026Article
- Impaction Predictors and Diagnostic Performance of CBCT Versus Panoramic Radiography for Supernumerary Teeth in a Romanian Multicenter Cohort.Diagnostics (Basel, Switzerland) · 2025Article
- Impaction of Deciduous and Permanent Teeth Related to Local Obstacles: A Retrospective Study of 10 Years of Institutional Experience.Children (Basel, Switzerland) · 2025Article
- Familial multiple impacted supernumerary teeth: Case report.The Journal of international medical research · 2025Article
- Molecular Biological Comparison of Pulp Stem Cells from Supernumerary Teeth, Permanent Teeth, and Deciduous Teeth for Endodontic Regeneration.International journal of molecular sciences · 2025Article
- Article
- Clinical and Radiographic Features of Mandibular Third Molar Gemination: A Case Report and Literature Review.Case reports in dentistry · 2025Article
- Impacted supernumerary tooth in the horizontal plate of palatine bone: a rare case report.BMC oral health · 2024Article
- Prevalence, Occurrence, and Characteristics of Supernumerary Teeth Among the Saudi Arabian Population Using Panoramic Radiographs.Diagnostics (Basel, Switzerland) · 2024Article
- Article
- Post-surgical complications of supernumerary teeth in the mandibular premolar area: A systematic review.Heliyon · 2024Article
- Investigation of the fungiform papillae number in children with tooth number anomalies.Clinical oral investigations · 2024Article
- Assessing the Efficacy of AI Segmentation in Diagnostics of Nine Supernumerary Teeth in a Pediatric Patient.Diagnostics (Basel, Switzerland) · 2023Article
- Supernumerary Tooth Patterns in Non-Syndromic White European Subjects.Dentistry journal · 2023Article
Corrections and comments
- Erratum issuedErratum.2018
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Supernumerary teeth are common clinical dental anomalies. Although various studies have provided abundant information regarding genes and signaling pathways involved in tooth morphogenesis, which include Wnt, FGF, BMP, and Shh, the molecular mechanism of tooth formation, especially for supernumerary teeth, is still unclear. In the population, some cases of supernumerary teeth are sporadic, while others are syndrome-related with familial hereditary. The prompt and accurate diagnosis of syndrome related supernumerary teeth is quite important for some distinctive disorders. Mice are the most commonly used model system for investigating supernumerary teeth. The upregulation of Wnt and Shh signaling in the dental epithelium results in the formation of multiple supernumerary teeth in mice. Understanding the molecular mechanism of supernumerary teeth is also a component of understanding tooth formation in general and provides clinical guidance for early diagnosis and treatment in the future.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.