Evidence map›Paper›PMID 28597831›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2017

Ongoing haemolytic uraemic syndrome (HUS) outbreak caused by sorbitol-fermenting (SF) Shiga toxin-producing Escherichia coli (STEC) O157, Germany, December 2016 to May 2017.

Sabine Vygen-Bonnet, Bettina Rosner, Hendrik Wilking, Angelika Fruth, Rita Prager, Annelene Kossow, Christina Lang, Sandra Simon, Juliane Seidel, Mirko Faber and 9 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Rise in the number of notifications of Shiga toxin-producingEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Shiga toxin-producingAccess microbiology · 2019
    Article
  6. Haemolytic uremic syndrome surveillance in children less than 15 years in Belgium, 2009-2015.Archives of public health = Archives belges de sante publique · 2018
    Article
  7. Sorbitol-Fermenting Enterohemorrhagic Escherichia coli O157:HApplied and environmental microbiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Sabine Vygen-BonnetRobert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany.
Bettina RosnerRobert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany.
Hendrik WilkingRobert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany.
Angelika FruthRobert Koch-Institute, Department of Infectious Diseases, National Reference Centre for Salmonella and other Bacterial Enteric Pathogens, Wernigerode, Germany.
Rita PragerRobert Koch-Institute, Department of Infectious Diseases, National Reference Centre for Salmonella and other Bacterial Enteric Pathogens, Wernigerode, Germany.
Annelene KossowUniversity Hospital of Münster, Consultant Laboratory for HUS, Münster, Germany.
Christina LangRobert Koch-Institute, Department of Infectious Diseases, National Reference Centre for Salmonella and other Bacterial Enteric Pathogens, Wernigerode, Germany.
Sandra SimonRobert Koch-Institute, Department of Infectious Diseases, National Reference Centre for Salmonella and other Bacterial Enteric Pathogens, Wernigerode, Germany.
Juliane SeidelRobert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany.
Mirko FaberRobert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany.
Anika SchielkeRobert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany.
Kai MichaelisRobert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany.
Alexandra HolzerRobert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany.
Rolf KamphausenMinistry of Climate Protection, Environment, Agriculture, Nature Conservation and Consumer Protection of the state of North Rhine-Westphalia, Düsseldorf, Germany.
Daniela KalhöferNorth Rhine-Westphalia, Centre for Health, Department of Infectiology and Hygiene, Münster, Germany.
Sebastian TholeEuropean Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Alexander MellmannUniversity Hospital of Münster, Consultant Laboratory for HUS, Münster, Germany.
Antje FliegerRobert Koch-Institute, Department of Infectious Diseases, National Reference Centre for Salmonella and other Bacterial Enteric Pathogens, Wernigerode, Germany.
Klaus StarkRobert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report an ongoing, protracted and geographically dispersed outbreak of haemolytic uraemic syndrome (HUS) and gastroenteritis in Germany, involving 30 cases since December 2016. The outbreak was caused by the sorbitol-fermenting immotile variant of Shiga toxin-producing (STEC) Escherichia coli O157. Molecular typing revealed close relatedness between isolates from 14 cases. One HUS patient died. Results of a case-control study suggest packaged minced meat as the most likely food vehicle. Food safety investigations are ongoing.

Indexed as

Disease OutbreaksCase-Control StudiesChildChild, PreschoolElectrophoresis, Gel, Pulsed-FieldEscherichia coli InfectionsEscherichia coli O157FemaleGastroenteritisGermanyHemolytic-Uremic SyndromeHumansInfantInfant, NewbornMeatSerotypingSorbitolfood-borne infectionshaemolytic uraemic syndromeHUSoutbreakShiga toxin-producing E. coli - STEC

Identifiers

PMID28597831
PMCPMC5479985

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.