Evidence map›Paper›PMID 28597557›Full record

ReviewMovement disorders : official journal of the Movement Disorder Society2017

Adaptive Deep Brain Stimulation for Movement Disorders: The Long Road to Clinical Therapy.

Anders Christian Meidahl, Gerd Tinkhauser, Damian Marc Herz, Hayriye Cagnan, Jean Debarros, Peter Brown

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Movement disorders : official journal of the Movement Disorder Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Clinical neurophysiological interrogation of motor slowing: A critical step towards tuning adaptive deep brain stimulation.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023
    Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anders Christian MeidahlMedical Research Council Brain Network Dynamics Unit at the University of Oxford, Oxford, UK.
Gerd TinkhauserMedical Research Council Brain Network Dynamics Unit at the University of Oxford, Oxford, UK.
Damian Marc HerzNuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.
Hayriye CagnanMedical Research Council Brain Network Dynamics Unit at the University of Oxford, Oxford, UK.
Jean DebarrosMedical Research Council Brain Network Dynamics Unit at the University of Oxford, Oxford, UK.
Peter BrownMedical Research Council Brain Network Dynamics Unit at the University of Oxford, Oxford, UK.

Funding

Department of HealthMedical Research Council MC_UU_12024/1Medical Research Council MR/M014762/1
6 · The paper itself

Abstract

Continuous high-frequency DBS is an established treatment for essential tremor and Parkinson's disease. Current developments focus on trying to widen the therapeutic window of DBS. Adaptive DBS (aDBS), where stimulation is dynamically controlled by feedback from biomarkers of pathological brain circuit activity, is one such development. Relevant biomarkers may be central, such as local field potential activity, or peripheral, such as inertial tremor data. Moreover, stimulation may be directed by the amplitude or the phase (timing) of the biomarker signal. In this review, we evaluate existing aDBS studies as proof-of-principle, discuss their limitations, most of which stem from their acute nature, and propose what is needed to take aDBS into a chronic setting. © 2017 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.

Indexed as

Deep Brain StimulationHumansMovement Disordersbrain-computer interfaceclosed-loopdeep brain stimulationessential tremorParkinson's disease

Identifiers

PMID28597557
PMCPMC5482397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.