ArticleBrain imaging and behavior2018
Brain reward responses to food stimuli among female monozygotic twins discordant for BMI.
Article in Brain imaging and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02025595 (The Role of Central Reward and Satiety Centers in the Etiology of Obesity), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Central Reward and Satiety Centers in the Etiology of Obesity: Genetic and Environmental Influences
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Neural correlates of uncertainty processing: meta-analysis of fMRI studies.Frontiers in neuroscience · 2025Pooled it
- Hunger and BMI modulate neural responses to sweet stimuli: fMRI meta-analysis.International journal of obesity (2005) · 2020Pooled it
- Trial
- Combination therapy with exenatide decreases the dapagliflozin-induced changes in brain responses to anticipation and consumption of palatable food in patients with type 2 diabetes: A randomized controlled trial.Diabetes, obesity & metabolism · 2022Trial
- Brain Activation in Response to Low-Calorie Food Pictures: An Explorative Analysis of a Randomized Trial With Dapagliflozin and Exenatide.Frontiers in endocrinology · 2022Trial
- Reviewing Physiological Measures of Implicit Consumer Response to Food.Foods (Basel, Switzerland) · 2026Review
- Restriction spectrum imaging reveals brain microstructural correlates of obesity risk in early childhood.Scientific reports · 2026Article
- Brain Microstructure and Obesity Risk in Early Childhood: Insights from Restriction Spectrum Imaging.bioRxiv : the preprint server for biology · 2025Article
- Intestinal short-chain fatty acid turnover is not associated with resting state functional connectivity in mesolimbic dopaminergic network in healthy adults.Neuroimage. Reports · 2025Article
- Epigenetic age acceleration in peripheral blood correlates with brain-MRI age acceleration.Brain : a journal of neurology · 2025Article
- Intestinal acetate and butyrate availability is associated with glucose metabolism in healthy individuals.iScience · 2023Article
- Article
- Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions.Molecular psychiatry · 2023Review
- Food cue reactivity: Neurobiological and behavioral underpinnings.Reviews in endocrine & metabolic disorders · 2022Review
- Brain Responses to High-Calorie Visual Food Cues in Individuals with Normal-Weight or Obesity: An Activation Likelihood Estimation Meta-Analysis.Brain sciences · 2021Review
- Reassessing relationships between appetite and adiposity in people at risk of obesity: A twin study using fMRI.Physiology & behavior · 2021Article
- Association of Disinhibited Eating and Trait of Impulsivity With Insula and Amygdala Responses to Palatable Liquid Consumption.Frontiers in systems neuroscience · 2021Article
- Is obesity related to enhanced neural reactivity to visual food cues? A review and meta-analysis.Social cognitive and affective neuroscience · 2020Article
- FTO genotype impacts food intake and corticolimbic activation.The American journal of clinical nutrition · 2018Observational
- What Twin Studies Tell Us About Brain Responses to Food Cues.Current obesity reports · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Obese individuals are characterized by altered brain reward responses to food. Despite the latest discovery of obesity-associated genes, the contribution of environmental and genetic factors to brain reward responsiveness to food remains largely unclear. Sixteen female monozygotic twin pairs with a mean BMI discordance of 3.96 ± 2.1 kg/m CLINICAL TRIAL REGISTRATION NUMBER: NCT02025595.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.