ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2018
Energy conserving thermoregulatory patterns and lower disease severity in a bat resistant to the impacts of white-nose syndrome.
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
25 citing papers in PubMed, 56 citations in OpenAlex.
- Bat skin microbiome and the association of ecoregion and bat species that impacted isolation of members with bioactivity against Pseudogymnoascus destructans.Animal microbiome · 2026Article
- Occupancy and activity patterns of a newly white-nose syndrome infected species in Texas, the Tricolored Bat (Journal of mammalogy · 2026Article
- Winter torpor and body mass patterns of a cave-roosting bat in cool and warm climates.Oecologia · 2025Article
- Winter activity of tricolored bats in aboveground and subterranean hibernacula in the southeastern USA.Scientific reports · 2025Article
- Vulnerability of Southern Hemisphere bats to white-nose syndrome based on global analysis of fungal host specificity and cave temperatures.Conservation biology : the journal of the Society for Conservation Biology · 2025Article
- White adipose tissue remodeling in Little Brown Myotis (Myotis lucifugus) with white-nose syndrome.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- The skin I live in: Pathogenesis of white-nose syndrome of bats.PLoS pathogens · 2024Review
- Capture rates ofEcology and evolution · 2024Article
- Hibernating female big brown bats (Eptesicus fuscus) adjust huddling and drinking behaviour, but not arousal frequency, in response to low humidity.The Journal of experimental biology · 2024Article
- Long-term spring through fall capture data ofData in brief · 2023Article
- Temperature shifts associated with bat arousals during hibernation inhibit the growth ofRoyal Society open science · 2022Article
- Experimental inoculation trial to determine the effects of temperature and humidity on White-nose Syndrome in hibernating bats.Scientific reports · 2022Article
- Disease tolerance alters host competence in a wild songbird.Biology letters · 2021Article
- Skin fungal assemblages of bats vary based on susceptibility to white-nose syndrome.The ISME journal · 2021Article
- Ecology and impacts of white-nose syndrome on bats.Nature reviews. Microbiology · 2021Review
- Transcriptional host-pathogen responses ofVirulence · 2020Article
- COUNTCOLORS, AN R PACKAGE FOR QUANTIFICATION OF THE FLUORESCENCE EMITTED BY PSEUDOGYMNOASCUS DESTRUCTANS LESIONS ON THE WING MEMBRANES OF HIBERNATING BATS.Journal of wildlife diseases · 2020Article
- Antifungal Potential of the Skin Microbiota of Hibernating Big Brown Bats (Frontiers in microbiology · 2020Article
- Article
- Multiscale model of regional population decline in little brown bats due to white-nose syndrome.Ecology and evolution · 2019Article
Corrections and comments
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Authors and funding
22 authors at 9 institutions in 1 country.
Funding
Abstract
The devastating bat fungal disease, white-nose syndrome (WNS), does not appear to affect all species equally. To experimentally determine susceptibility differences between species, we exposed hibernating naïve little brown myotis (Myotis lucifugus) and big brown bats (Eptesicus fuscus) to the fungus that causes WNS, Pseudogymnoascus destructans (Pd). After hibernating under identical conditions, Pd lesions were significantly more prevalent and more severe in little brown myotis. This species difference in pathology correlates with susceptibility to WNS in the wild and suggests that survival is related to different host physiological responses. We observed another fungal infection, associated with neutrophilic inflammation, that was equally present in all bats. This suggests that both species are capable of generating a response to cold tolerant fungi and that Pd may have evolved mechanisms for evading host responses that are effective in at least some bat species. These host-pathogen interactions are likely mediated not just by host physiological responses, but also by host behavior. Pd-exposed big brown bats, the less affected species, spent more time in torpor than did control animals, while little brown myotis did not exhibit this change. This differential thermoregulatory response to Pd infection by big brown bat hosts may allow for a more effective (or less pathological) immune response to tissue invasion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.