Evidence map›Paper›PMID 28597075›Full record

ArticleDiabetologia2017

Improved pregnancy outcomes in women with type 1 and type 2 diabetes but substantial clinic-to-clinic variations: a prospective nationwide study.

Helen R Murphy, Ruth Bell, Cher Cartwright, Paula Curnow, Michael Maresh, Margery Morgan, Catherine Sylvester, Bob Young, Nick Lewis-Barned

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04902378 (Closed-loop Insulin Delivery by Glucose Responsive Computer Algorithms In Type 1 Diabetes Pregnancies), which is not on this map. Cited by 81 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 5 pooled it
20.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04902378 nacompletednot on this mapstarted 2021, after this paper: background citation

Closed-loop Insulin Delivery by Glucose Responsive Computer Algorithms In Type 1 Diabetes Pregnancies (CIRCUIT)

TypeinterventionalSponsorUniversity of CalgaryRan2021 to 2025Enrolled94ConditionsType 1 Diabetes Mellitus, Pregnancy Related, Glucose Metabolism Disorders, Metabolic DiseaseArmsTandem t:slim X2 insulin pump with Control IQ technology
3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 5 syntheses or guidelines pooled it, 216 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Helen R MurphyNorwich Medical School, Floor 2, Bob Champion Research and Education Building, University of East Anglia, Norwich, NR4 7UQ, UK. helen.murphy@uea.ac.uk.
Ruth BellInstitute of Health and Society, Newcastle University, Newcastle upon Tyne, UK.
Cher CartwrightClinical Audits & Registries Management Service, NHS Digital, Leeds, UK.
Paula CurnowClinical Audits & Registries Management Service, NHS Digital, Leeds, UK.
Michael MareshDepartment of Obstetrics, St Mary's Hospital, Central Manchester University Hospital NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Margery MorganDepartment of Obstetrics, Singleton Hospital, Abertawe Bro Morgannwg, Swansea, UK.
Catherine SylvesterClinical Audits & Registries Management Service, NHS Digital, Leeds, UK.
Bob YoungClinical Audits & Registries Management Service, NHS Digital, Leeds, UK.
Nick Lewis-BarnedDepartment of Diabetes and Endocrinology, Northumbria Healthcare NHS Foundation Trust, Northumberland, UK.
NHS Digital · GBManchester Academic Health Science Centre · GBNewcastle University · GBNorthumbria Healthcare NHS Foundation Trust · GBSingleton Hospital · GBUniversity of East Anglia · GB

Funding

Department of Health CDF-2013-06-035Medical Research Council MR/K02325X/1
6 · The paper itself

Abstract

aims/hypothesisThe aim of this prospective nationwide study was to examine antenatal pregnancy care and pregnancy outcomes in women with type 1 and type 2 diabetes, and to describe changes since 2002/2003.

methodsThis national population-based cohort included 3036 pregnant women with diabetes from 155 maternity clinics in England and Wales who delivered during 2015. The main outcome measures were maternal glycaemic control, preterm delivery (before 37 weeks), infant large for gestational age (LGA), and rates of congenital anomaly, stillbirth and neonatal death.

resultsOf 3036 women, 1563 (51%) had type 1, 1386 (46%) had type 2 and 87 (3%) had other types of diabetes. The percentage of women achieving HbA CONCLUSIONS/

interpretationStillbirth rates among women with type 1 and type 2 diabetes have decreased since 2002/2003. Rates of preterm delivery and LGA infants are lower in women with type 2 compared with type 1 diabetes. In women with type 1 diabetes, suboptimal glucose control and high rates of perinatal morbidity persist with substantial variations between clinics. DATA AVAILABILITY: Further details of the data collection methodology, individual clinic data and the full audit reports for healthcare professionals and service users are available from http://content.digital.nhs.uk/npid .

Indexed as

AdultDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleHumansPregnancyPregnancy OutcomePremature BirthProspective StudiesStillbirthYoung AdultAntenatalCongenital anomalyDiabetesGlucoseLarge for gestational ageNeonatalPregnancyPre-pregnancy carePretermStillbirth

Identifiers

PMID28597075
PMCPMC5552835
OpenAlexW2622457820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.