Evidence map›Paper›PMID 28596957›Full record

ArticleFrontiers in cardiovascular medicine2017

Heterogeneous Vascular Bed Responses to Pulmonary Titanium Dioxide Nanoparticle Exposure.

Alaeddin B Abukabda, Phoebe A Stapleton, Carroll R McBride, Jinghai Yi, Timothy R Nurkiewicz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Nanomaterial Inhalation During Pregnancy Alters Systemic Vascular Function in a Cyclooxygenase-Dependent Manner.Toxicological sciences : an official journal of the Society of Toxicology · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Maternal Engineered Nanomaterial Inhalation During Gestation Disrupts Vascular Kisspeptin Reactivity.Toxicological sciences : an official journal of the Society of Toxicology · 2019
    Article
  13. Article
  14. Article
  15. Microvascular Dysfunction Following Multiwalled Carbon Nanotube Exposure Is Mediated by Thrombospondin-1 Receptor CD47.Toxicological sciences : an official journal of the Society of Toxicology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alaeddin B AbukabdaDepartment of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, WV, USA.
Phoebe A StapletonDepartment of Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA.
Carroll R McBrideDepartment of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, WV, USA.
Jinghai YiDepartment of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, WV, USA.
Timothy R NurkiewiczDepartment of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, WV, USA.
West Virginia University · USRutgers, The State University of New Jersey · US

Funding

Remote Microvascular Dysfunction After Particulate Matter ExposureR01ES015022 · NIEHS · WEST VIRGINIA UNIVERSITY · PI NURKIEWICZ, TIMOTHY R · 2007 to 2021
$4.9M
Mitochondrial Mechanisms, Microvascular Function, and Gestational NanotoxicologyR00ES024783 · NIEHS · RUTGERS, THE STATE UNIV OF N.J. · PI STAPLETON, PHOEBE · 2017 to 2019
$747k
Mitochondrial Mechanisms, Microvascular Function, and Gestational NanotoxicologyK99ES024783 · NIEHS · WEST VIRGINIA UNIVERSITY · PI STAPLETON, PHOEBE · 2015 to 2016
$172k
NIEHS NIH HHS K99 ES024783NIEHS NIH HHS R00 ES024783NIEHS NIH HHS R01 ES015022
6 · The paper itself

Abstract

A growing body of research links engineered nanomaterial (ENM) exposure to adverse cardiovascular endpoints. The purpose of this study was to evaluate the impact of ENM exposure on vascular reactivity in discrete segments so that we may determine the most sensitive levels of the vasculature where these negative cardiovascular effects are manifest. We hypothesized that acute nano-TiO

Indexed as

cardiovascular systemendotheliumengineered nanomaterialsmicrocirculationtitanium dioxide

Identifiers

PMID28596957
PMCPMC5442182
OpenAlexW2618125537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.