Evidence map›Paper›PMID 28596940›Full record

ArticleFrontiers in oncology2017

Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca

Luca Hegedüs, Rita Padányi, Judit Molnár, Katalin Pászty, Karolina Varga, István Kenessey, Eszter Sárközy, Matthias Wolf, Michael Grusch, Zoltán Hegyi and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. A role for plasma membrane CaPflugers Archiv : European journal of physiology · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The Plasma Membrane CaCancers · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Endoplasmic Reticulum Calcium Pumps and Tumor Cell Differentiation.International journal of molecular sciences · 2020
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Luca HegedüsDepartment of Thoracic Surgery, Ruhrlandklinik, University Clinic Essen, Essen, Germany.
Rita Padányi2nd Institute of Pathology, Semmelweis University, Budapest, Hungary.
Judit Molnár2nd Institute of Pathology, Semmelweis University, Budapest, Hungary.
Katalin PásztyMolecular Biophysics Research Group of the Hungarian Academy of Sciences, Department of Biophysics, Semmelweis University, Budapest, Hungary.
Karolina Varga2nd Institute of Pathology, Semmelweis University, Budapest, Hungary.
István Kenessey2nd Institute of Pathology, Semmelweis University, Budapest, Hungary.
Eszter Sárközy2nd Institute of Pathology, Semmelweis University, Budapest, Hungary.
Matthias WolfDepartment of Medicine I, Institute of Cancer Research, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria.
Michael GruschDepartment of Medicine I, Institute of Cancer Research, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria.
Zoltán HegyiInstitute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary.
László HomolyaInstitute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary.
Clemens AignerDepartment of Thoracic Surgery, Ruhrlandklinik, University Clinic Essen, Essen, Germany.
Tamás GarayMolecular Oncology Research Group of the Hungarian Academy of Sciences, Semmelweis University, Budapest, Hungary.
Balázs HegedüsDepartment of Thoracic Surgery, Ruhrlandklinik, University Clinic Essen, Essen, Germany.
József Tímár2nd Institute of Pathology, Semmelweis University, Budapest, Hungary.
Enikö KállayDepartment of Pathophysiology and Allergy Research, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria.
Ágnes Enyedi2nd Institute of Pathology, Semmelweis University, Budapest, Hungary.
Hungarian Academy of Sciences · HUSemmelweis University · HUComprehensive Cancer Center Vienna · ATMedical University of Vienna · ATRuhrlandklinik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several new therapeutic options emerged recently to treat metastatic melanoma; however, the high frequency of intrinsic and acquired resistance among patients shows a need for new therapeutic options. Previously, we identified the plasma membrane Ca

Indexed as

BRAF-mutant melanomacell motilityHDAC inhibitorsPMCA1PMCA4

Identifiers

PMID28596940
PMCPMC5442207
OpenAlexW2618023968

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.