Evidence map›Paper›PMID 28596681›Full record

ArticleWorld journal of gastroenterology2017

Effects of heme oxygenase-1-modified bone marrow mesenchymal stem cells on microcirculation and energy metabolism following liver transplantation.

Liu Yang, Zhong-Yang Shen, Rao-Rao Wang, Ming-Li Yin, Wei-Ping Zheng, Bin Wu, Tao Liu, Hong-Li Song

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Zn-Incorporated TiOInternational journal of nanomedicine · 2020
    Article
  12. Review
  13. [Research progress in mesenchymal stem cells modified by Heme oxygenase 1].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2019
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Liu YangLiu Yang, Rao-Rao Wang, Ming-Li Yin, the First Central Clinical College Tianjin Medical University, Tianjin 300070, China.
Zhong-Yang ShenLiu Yang, Rao-Rao Wang, Ming-Li Yin, the First Central Clinical College Tianjin Medical University, Tianjin 300070, China.
Rao-Rao WangLiu Yang, Rao-Rao Wang, Ming-Li Yin, the First Central Clinical College Tianjin Medical University, Tianjin 300070, China.
Ming-Li YinLiu Yang, Rao-Rao Wang, Ming-Li Yin, the First Central Clinical College Tianjin Medical University, Tianjin 300070, China.
Wei-Ping ZhengLiu Yang, Rao-Rao Wang, Ming-Li Yin, the First Central Clinical College Tianjin Medical University, Tianjin 300070, China.
Bin WuLiu Yang, Rao-Rao Wang, Ming-Li Yin, the First Central Clinical College Tianjin Medical University, Tianjin 300070, China.
Tao LiuLiu Yang, Rao-Rao Wang, Ming-Li Yin, the First Central Clinical College Tianjin Medical University, Tianjin 300070, China.
Hong-Li SongLiu Yang, Rao-Rao Wang, Ming-Li Yin, the First Central Clinical College Tianjin Medical University, Tianjin 300070, China.
Tianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effects of heme oxygenase-1 (HO-1)-modified bone marrow mesenchymal stem cells (BMMSCs) on the microcirculation and energy metabolism of hepatic sinusoids following reduced-size liver transplantation (RLT) in a rat model.

methodsBMMSCs were isolated and cultured

resultsHO-1/BMMSCs could alleviate the pathological changes and rejection activity index of the transplanted liver, and improve the liver function of rats following 50% RLT, with statistically significant differences compared with those of the NS group and BMMSCs group (

conclusionHO-1/BMMSCs can improve the microcirculation of hepatic sinusoids significantly, and recover the energy metabolism of damaged hepatocytes in rats following RLT, thus protecting the transplanted liver.

Indexed as

Energy MetabolismLiver TransplantationAdenoviridaeAdipocytesAdipogenesisAnimalsBone Marrow CellsCapillariesCell DifferentiationEndothelin-1Graft RejectionHeme Oxygenase (Decyclizing)LiverLiver Function TestsMaleMesenchymal Stem CellsEndothelin-1Heme Oxygenase (Decyclizing)Hmox1 protein, ratNitric OxideNitric Oxide Synthase Type IINitric Oxide Synthase Type IIINos2 protein, ratNos3 protein, ratvon Willebrand FactorBone marrow mesenchymal stem cellsEnergy metabolismHeme oxygenase-1MicrocirculationReduced-size liver transplantation

Identifiers

PMID28596681
PMCPMC5442081
OpenAlexW2615574976

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.