Evidence map›Paper›PMID 28596646›Full record

ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2017

Evaluation of Bone Marrow Microvessel Density in Patients with Aplastic Anemia.

Venkatesan Somasundaram, Manvir Singh Tevatia, Abhishek Purohit, Ankur Ahuja, Manoranjan Mahapatra, Seema Tyagi, Haraprasad Pati, Renu Saxena

Abstract read
In one paragraph

Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Role of the microenvironment in myeloid malignancies.Cellular and molecular life sciences : CMLS · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Venkatesan SomasundaramDepartment of Pathology, Armed Forces Medical College, Pune, 411040 India.
Manvir Singh TevatiaBrig Med, HQ Delhi Area, New Delhi, India.
Abhishek PurohitDepartment of Pathology, All India Institute of Medical Sciences, Jodhpur, India.
Ankur AhujaDepartment of Hematology, All India Institute of Medical Sciences, New Delhi, India.
Manoranjan MahapatraDepartment of Hematology, All India Institute of Medical Sciences, New Delhi, India.
Seema TyagiDepartment of Hematology, All India Institute of Medical Sciences, New Delhi, India.
Haraprasad PatiDepartment of Hematology, All India Institute of Medical Sciences, New Delhi, India.
Renu SaxenaDepartment of Hematology, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · INAll India Institute of Medical Sciences Jodhpur · INArmed Forces Medical College · INUniversity College of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone marrow microenvironment plays a crucial role in the growth of hemopoietic cells and bone marrow function, which in turn depends on an intact microvasculature. Our study assesses the microvessel density (MVD) in the bone marrow of aplastic anemia (AA) patients, compares with MVD of controls and MVD among the different types of AA. Bone marrow specimens from 60 patients with AA and 17 controls were studied. There were 33 patients with non severe AA (NSAA), 12 patients with severe AA (SAA) and 15 patients with very severe AA (VSAA). MVD was calculated on sections stained immunohistochemically for CD34. The mean bone marrow MVD in AA group was 1.28 ± 0.36, being significantly lower than that in control group (6.80 ± 1.59,

Indexed as

AngiogenesisAplastic anemiaCD 34Mean vascular density (MVD)

Identifiers

PMID28596646
PMCPMC5442054
OpenAlexW2482628036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.