Evidence map›Paper›PMID 28596519›Full record

ArticleScientific reports2017

The Connection of the Genetic, Cultural and Geographic Landscapes of Transoxiana.

Maxat Zhabagin, Elena Balanovska, Zhaxylyk Sabitov, Marina Kuznetsova, Anastasiya Agdzhoyan, Olga Balaganskaya, Marina Chukhryaeva, Nadezhda Markina, Alexey Romanov, Roza Skhalyakho and 10 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Maxat ZhabaginNational Laboratory Astana, Nazarbayev University, Astana, Republic of Kazakhstan. mzhabagin@gmail.com.ORCID 0000-0003-3414-0610
Elena BalanovskaResearch Centre for Medical Genetics, Moscow, Russia.
Zhaxylyk SabitovL.N.Gumilyov Eurasian National University, Astana, Republic of Kazakhstan.
Marina KuznetsovaResearch Centre for Medical Genetics, Moscow, Russia.
Anastasiya AgdzhoyanVavilov Institute for General Genetics, Russian Academy of Sciences, Moscow, Russia.
Olga BalaganskayaVavilov Institute for General Genetics, Russian Academy of Sciences, Moscow, Russia.
Marina ChukhryaevaVavilov Institute for General Genetics, Russian Academy of Sciences, Moscow, Russia.ORCID 0000-0002-8372-1043
Nadezhda MarkinaVavilov Institute for General Genetics, Russian Academy of Sciences, Moscow, Russia.
Alexey RomanovResearch Centre for Medical Genetics, Moscow, Russia.
Roza SkhalyakhoVavilov Institute for General Genetics, Russian Academy of Sciences, Moscow, Russia.
Valery ZaporozhchenkoVavilov Institute for General Genetics, Russian Academy of Sciences, Moscow, Russia.
Liudmila SaroyantsLeprosy Research Institute, Astrakhan, Russia.
Dilbar DalimovaInstitute of Bioorganic Chemistry, Tashkent, Uzbekistan.
Damir DavletchurinInstitute of Bioorganic Chemistry, Tashkent, Uzbekistan.
Shahlo TurdikulovaCenter of High Technologies, Tashkent, Uzbekistan.
Yuldash YusupovInstitute of Strategic Research of the Republic of Bashkortostan, Ufa, Russia.
Inkar TazhigulovaForensic science centre of the Ministry of Justice of the Republic of Kazakhstan, Astana, Republic of Kazakhstan.
Ainur AkilzhanovaNational Laboratory Astana, Nazarbayev University, Astana, Republic of Kazakhstan.
Chris Tyler-SmithThe Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Oleg BalanovskyResearch Centre for Medical Genetics, Moscow, Russia. balanovsky@inbox.ru.

Funding

Wellcome Trust
6 · The paper itself

Abstract

We have analyzed Y-chromosomal variation in populations from Transoxiana, a historical region covering the southwestern part of Central Asia. We studied 780 samples from 10 regional populations of Kazakhs, Uzbeks, Turkmens, Dungans, and Karakalpaks using 35 SNP and 17 STR markers. Analysis of haplogroup frequencies using multidimensional scaling and principal component plots, supported by an analysis of molecular variance, showed that the geographic landscape of Transoxiana, despite its distinctiveness and diversity (deserts, fertile river basins, foothills and plains) had no strong influence on the genetic landscape. The main factor structuring the gene pool was the mode of subsistence: settled agriculture or nomadic pastoralism. Investigation of STR-based clusters of haplotypes and their ages revealed that cultural and demic expansions of Transoxiana were not closely connected with each other. The Arab cultural expansion introduced Islam to the region but did not leave a significant mark on the pool of paternal lineages. The Mongol expansion, in contrast, had enormous demic success, but did not impact cultural elements like language and religion. The genealogy of Muslim missionaries within the settled agricultural communities of Transoxiana was based on spiritual succession passed from teacher to disciple. However, among Transoxianan nomads, spiritual and biological succession became merged.

Indexed as

CultureGenetics, PopulationAsia, CentralChromosomes, Human, YCluster AnalysisGeographyHaplotypesHuman MigrationHumansPaternal InheritancePolymorphism, Single NucleotidePopulation Groups

Identifiers

PMID28596519
PMCPMC5465200

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.