Evidence map›Paper›PMID 28596334›Full record

ReviewScience (New York, N.Y.)2017

Self-repairing cells: How single cells heal membrane ruptures and restore lost structures.

Sindy K Y Tang, Wallace F Marshall

Abstract readReview
In one paragraph

Review in Science (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Article
  2. A role for theMolecular biology of the cell · 2026
    Article
  3. Article
  4. Article
  5. A role for thebioRxiv : the preprint server for biology · 2025
    Article
  6. Characterization of cellular wound resistance in the giant ciliatebioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Review
  9. Membrane Tension Regulation is Required for Wound Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Cell-based carrier for targeted hitchhiking delivery.Drug delivery and translational research · 2022
    Review
  18. Article
  19. Article
  20. International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sindy K Y TangDepartment of Mechanical Engineering, Stanford University, Stanford, CA, USA. sindy@stanford.edu wallace.marshall@ucsf.edu.ORCID 0000-0003-1465-2432
Wallace F MarshallDepartment of Biochemistry and Biophysics, University of California-San Francisco, San Francisco, CA, USA. sindy@stanford.edu wallace.marshall@ucsf.edu.ORCID 0000-0002-8467-5763

Funding

Pattern formation and regeneration in a single cellR01GM113602 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARSHALL, WALLACE · 2015 to 2018
$1.6M
NIGMS NIH HHS R01 GM113602
6 · The paper itself

Abstract

Many organisms and tissues display the ability to heal and regenerate as needed for normal physiology and as a result of pathogenesis. However, these repair activities can also be observed at the single-cell level. The physical and molecular mechanisms by which a cell can heal membrane ruptures and rebuild damaged or missing cellular structures remain poorly understood. This Review presents current understanding in wound healing and regeneration as two distinct aspects of cellular self-repair by examining a few model organisms that have displayed robust repair capacity, including

Indexed as

RegenerationAnimalsCiliophoraEukaryotaWound HealingXenopus

Identifiers

PMID28596334
PMCPMC5664224

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.