Evidence map›Paper›PMID 28596300›Full record

ArticlePhysiological reports2017

Clear Cell Renal Cell Carcinoma is linked to Epithelial-to-Mesenchymal Transition and to Fibrosis.

Lea Landolt, Øystein Eikrem, Philipp Strauss, Andreas Scherer, David H Lovett, Christian Beisland, Kenneth Finne, Tarig Osman, Mohammad M Ibrahim, Gro Gausdal and 6 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 42 citations in OpenAlex.

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  13. Renal tumor biomarkers (Review).Experimental and therapeutic medicine · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 5 countries.

Lea LandoltDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Øystein EikremDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Philipp StraussDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Andreas SchererSpheromics, Kontiolahti, Finland.
David H LovettDepartment of Medicine, San Francisco VAMC University of California San Francisco, San Francisco, California.
Christian BeislandDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Kenneth FinneDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Tarig OsmanDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Mohammad M IbrahimDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Gro GausdalBerGenBio AS, Bergen, Norway.
Lavina AhmedBerGenBio AS, Bergen, Norway.
James B LorensBerGenBio AS, Bergen, Norway.
Jean Paul ThieryDepartment of Biomedicine, Center for Cancer Biomarkers University of Bergen, Bergen, Norway.
Tuan Zea TanScience Institute of Singapore National University of Singapore, Singapore, Singapore.
Miroslav SekulicDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Hans-Peter MartiDepartment of Clinical Medicine, University of Bergen, Bergen, Norway hans-peter.marti@uib.no.
University of Bergen · NOBerGenBio (Norway) · NONational University of Singapore · SGUniversity of California, San Francisco · USUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clear cell renal cell carcinoma (ccRCC) represents the most common type of kidney cancer with high mortality in its advanced stages. Our study aim was to explore the correlation between tumor epithelial-to-mesenchymal transition (EMT) and patient survival. Renal biopsies of tumorous and adjacent nontumorous tissue were taken with a 16 g needle from our patients (

Indexed as

Epithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticAdultAgedAxl Receptor Tyrosine KinaseCarcinoma, Renal CellFemaleFibrosisGlucuronidaseHumansKidneyKidney NeoplasmsKlotho ProteinsMaleMatrix Metalloproteinase 14MicroRNAsAXL protein, humanAxl Receptor Tyrosine KinaseGlucuronidaseKlotho ProteinsMatrix Metalloproteinase 14MicroRNAsMIRN34 microRNA, humanMMP14 protein, humanProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesClear cell renal cell carcinomaepithelial‐to‐mesenchymal transitionfibrosis

Identifiers

PMID28596300
PMCPMC5471444
OpenAlexW2622954435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.