Evidence map›Paper›PMID 28596281›Full record

Observational studyHaematologica2017

Hemoglobin concentration, total hemoglobin mass and plasma volume in patients: implications for anemia.

James M Otto, James O M Plumb, Eleri Clissold, Shriya B Kumar, Denis J Wakeham, Walter Schmidt, Michael P W Grocott, Toby Richards, Hugh E Montgomery

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.

  1. Pooled it
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  5. Crossing the line: blood transfusion thresholds in ECMO.Critical care (London, England) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

James M OttoDivision of Surgery and Interventional Science, University College London, UK.
James O M PlumbAnaesthesia and Critical Care Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Eleri ClissoldAnaesthesia and Critical Care Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Shriya B KumarAnaesthesia and Critical Care Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Denis J WakehamSchool of Sport, Physiology and Health Group, Cardiff Metropolitan University, UK.
Walter SchmidtDepartment of Sports Medicine/Sports Physiology, University of Bayreuth, Germany.
Michael P W GrocottAnaesthesia and Critical Care Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Toby RichardsDivision of Surgery and Interventional Science, University College London, UK toby.richards@ucl.ac.uk.
Hugh E MontgomeryCentre for Human Health and Performance/Institute of Sport, Exercise and Health, University College London, and NIHR University College London Hospitals Biomedical Research Centre, UK.
University College London · GBUniversity Hospital Southampton NHS Foundation Trust · GBCardiff Metropolitan University · GBNIHR Southampton Respiratory Biomedical Research Unit · GBUniversity of Bayreuth · DEUniversity of Southampton · GB

Funding

Department of Health 10/104/06Wellcome Trust
6 · The paper itself

Abstract

In practice, clinicians generally consider anemia (circulating hemoglobin concentration < 120 g.l

Indexed as

AnemiaHeart FailurePlasma VolumeAdultFemaleHemoglobinsHumansMaleMiddle AgedHemoglobins

Identifiers

PMID28596281
PMCPMC5685237
OpenAlexW2622357367

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.