Evidence map›Paper›PMID 28596192›Full record

Trial reportAJNR. American journal of neuroradiology2017

The Impact of Conscious Sedation versus General Anesthesia for Stroke Thrombectomy on the Predictive Value of Collateral Status: A Post Hoc Analysis of the SIESTA Trial.

S Schönenberger, J Pfaff, L Uhlmann, C Klose, S Nagel, P A Ringleb, W Hacke, M Kieser, M Bendszus, M A Möhlenbruch and 1 more

Open access · hybridAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Physiologic predictors of collateral circulation and infarct growth during anesthesia - Detailed analyses of the GOLIATH trial.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  4. Article
  5. Review
  6. Vascular medicine and thrombectomy in stroke.Therapeutic advances in neurological disorders · 2018
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

S SchönenbergerFrom the Departments of Neurology (S.S., S.N., P.A.R., W.H., J.B.) silvia.schoenenberger@med.uni-heidelberg.de.ORCID http://orcid.org/0000-0002-3348-6719
J PfaffNeuroradiology (J.P., M.B., M.A.M.), Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-0672-5718
L UhlmannInstitute of Medical Biometry and Informatics (L.U., C.K., M.K.), University of Heidelberg, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-8668-069X
C KloseInstitute of Medical Biometry and Informatics (L.U., C.K., M.K.), University of Heidelberg, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-3186-0500
S NagelFrom the Departments of Neurology (S.S., S.N., P.A.R., W.H., J.B.).ORCID http://orcid.org/0000-0003-2471-6647
P A RinglebFrom the Departments of Neurology (S.S., S.N., P.A.R., W.H., J.B.).ORCID http://orcid.org/0000-0002-5473-8671
W HackeFrom the Departments of Neurology (S.S., S.N., P.A.R., W.H., J.B.).ORCID http://orcid.org/0000-0002-6951-6182
M KieserInstitute of Medical Biometry and Informatics (L.U., C.K., M.K.), University of Heidelberg, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-2402-4333
M BendszusNeuroradiology (J.P., M.B., M.A.M.), Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-9094-6769
M A MöhlenbruchNeuroradiology (J.P., M.B., M.A.M.), Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-5075-704X
J BöselFrom the Departments of Neurology (S.S., S.N., P.A.R., W.H., J.B.).ORCID http://orcid.org/0000-0001-5428-0771
Norwegian Womens Public Health Association · NOHeidelberg University · DEZimmer Biomet (Netherlands) · NLHeidelbergCement (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeRadiologic selection criteria to identify patients likely to benefit from endovascular stroke treatment are still controversial. In this post hoc analysis of the recent randomized Sedation versus Intubation for Endovascular Stroke TreAtment (SIESTA) trial, we aimed to investigate the impact of sedation mode (conscious sedation versus general anesthesia) on the predictive value of collateral status. MATERIALS AND

methodsUsing imaging data from SIESTA, we assessed collateral status with the collateral score of Tan et al and graded it from absent to good collaterals (0-3). We examined the association of collateral status with 24-hour improvement of the NIHSS score, infarct volume, and mRS at 3 months according to the sedation regimen.

resultsIn a cohort of 104 patients, the NIHSS score improved significantly in patients with moderate or good collaterals (2-3) compared with patients with no or poor collaterals (0-1) (

conclusionsThe sedation mode, conscious sedation or general anesthesia, did not influence the predictive value of collaterals in patients with large-vessel occlusion anterior circulation stroke undergoing thrombectomy in the SIESTA trial.

Indexed as

Collateral CirculationAdultAgedAged, 80 and overAnesthesia, GeneralCerebral AngiographyCerebral InfarctionCerebrovascular CirculationCohort StudiesEndovascular ProceduresFemaleHumansMaleMiddle AgedPredictive Value of TestsProcedural Sedation

Identifiers

PMID28596192
PMCPMC7960428
OpenAlexW2622431577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.