Evidence map›Paper›PMID 28595735›Full record

ArticleAnnals of epidemiology2017

Sex-specific associations of maternal birthweight with offspring birthweight in the Omega study.

Collette N Ncube, Amelia R Gavin, Michelle A Williams, Chunfang Qiu, Tanya K Sorensen, Daniel A Enquobahrie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Collette N NcubeDepartment of Epidemiology, School of Public Health, University of Washington, Seattle. Electronic address: ncubec@u.washington.edu.
Amelia R GavinSchool of Social Work, University of Washington, Seattle.
Michelle A WilliamsCenter for Perinatal Studies, Swedish Medical Center, Seattle, WA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Chunfang QiuCenter for Perinatal Studies, Swedish Medical Center, Seattle, WA.
Tanya K SorensenCenter for Perinatal Studies, Swedish Medical Center, Seattle, WA.
Daniel A EnquobahrieDepartment of Epidemiology, School of Public Health, University of Washington, Seattle; Center for Perinatal Studies, Swedish Medical Center, Seattle, WA.

Funding

The Epidemiology of Marine Fatty Acids and PreeclampsiaR01HD032562 · NICHD · SWEDISH MEDICAL CENTER, FIRST HILL · PI WILLIAMS, MICHELLE A. · 1996 to 2006
$3.0M
University of Washington Reproductive, Perinatal and Pediatric Epidemiology T32HD052462 · NICHD · UNIVERSITY OF WASHINGTON · PI HOLT, VICTORIA L · 2006 to 2017
$2.7M
NICHD NIH HHS R01 HD032562NICHD NIH HHS T32 HD052462
6 · The paper itself

Abstract

purposeWe investigated nonlinear and offspring sex-specific associations of maternal birthweight (BW) with offspring BW among participants of the Omega study, a pregnancy cohort.

methodsMaternal BW was modeled as a continuous variable, linear spline and binary variable indicating low birthweight (LBW; <2500 vs. ≥2500 grams). Offspring BW was modeled as a continuous and binary variable in regression models. Nonlinearity was assessed using likelihood ratio tests (LRTs) in marginal linear spline models.

resultsFor every 100-gram increase of maternal BW, offspring BW increased by 22.29 (95% CI: 17.57, 27.02) or 23.41 (95% CI: 6.87, 39.96) grams among mothers with normal BW or born macrosomic, respectively, but not among LBW mothers (β = -8.61 grams; 95% CI: -22.88, 5.65; LRT P-value = .0005). For every 100-gram increase in maternal BW, BW of male offspring increased 23.47 (95% CI: 16.75, 30.19) or 25.21 (95% CI: 4.35, 46.07) grams among mothers with normal BW or born macrosomic, respectively, whereas it decreased 31.39 grams (95% CI: -51.63, -11.15) among LBW mothers (LRT P-value < .0001). Corresponding increases in BW of female offspring (16-22 grams) did not differ among mothers with LBW, normal BW or macrosomia (LRT P-value = .9163).

conclusionsMaternal and offspring BW associations are evident among normal BW and macrosomic mothers. These associations differ by offspring sex.

Indexed as

Body Mass IndexInfant, Low Birth WeightMothersAdultBirth WeightCohort StudiesFemaleHumansInfant, NewbornInterviews as TopicMalePregnancyPregnancy OutcomeSex FactorsSurveys and QuestionnairesWashingtonBirthweightBody mass indexInfantLow birthweightMothersPregnancySexWeight gain

Identifiers

PMID28595735
PMCPMC5548425

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.