Evidence map›Paper›PMID 28595669›Full record

ArticleEpidemiology and infection2017

Surges of advanced medical support associated with influenza outbreaks.

J C King, J E Schweinle, R J Hatchett, Y Gao, R Lichenstein, J Zhou

Abstract read
In one paragraph

Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Severe Illnesses Associated With Outbreaks of Respiratory Syncytial Virus and Influenza in Adults.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J C KingUS Department of Health and Human Services,Assistant Secretary for Preparedness and Response, Biomedical Advanced Research and Development Authority,Washington,DC 20201,USA.
J E SchweinleUS Department of Health and Human Services,Assistant Secretary for Preparedness and Response, Biomedical Advanced Research and Development Authority,Washington,DC 20201,USA.
R J HatchettCoalition for Epidemic Preparedness Innovations (CEPI), CEPI, c/o Norwegian Institute of Public Health,PB 4404 Nydalen,N-0403 Oslo,Norway.
Y GaoUS Department of Health and Human Services,Assistant Secretary for Preparedness and Response, Biomedical Advanced Research and Development Authority,Washington,DC 20201,USA.
R LichensteinDepartment of Pediatrics,University of Maryland School of Medicine,Baltimore,Maryland 21201,USA.
J ZhouUS Department of Health and Human Services,Assistant Secretary for Preparedness and Response, Biomedical Advanced Research and Development Authority,Washington,DC 20201,USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We utilized de-identified data to evaluate increases in four outcomes during influenza outbreak periods (IOPs) including: hospitalization, intensive care unit admission, mechanical ventilation or death for adults aged 18 years or older with medically attended acute respiratory illnesses (MAARI) admitted to any of Maryland's 50 acute-care hospitals over 12 years. Weekly numbers of positive influenza tests in the Maryland area were obtained from the US Center for Disease Control and Prevention interactive website. The fewest consecutive weeks around the peak week containing at least 85% of the positive tests defined the IOP. Weekly counts of individual study outcomes were positively correlated with regional weekly counts of positive influenza tests during all the IOPs over 12 years. Also, rate ratios comparing daily occurrences of each study outcome between the IOP and non-IOP were significantly elevated. These results confirm conclusions of previous studies that influenza outbreaks are clearly associated with deaths and increased use of advanced medical resources by patients with MAARI. These data analyses suggest that increased efforts to develop more effective influenza vaccines and therapeutics should be a priority.

Indexed as

Disease OutbreaksIntensive Care UnitsAdolescentAdultAgedAged, 80 and overFemaleHospitalizationHumansInfluenza, HumanMaleMarylandMiddle AgedRespiration, ArtificialYoung AdultDeathhospitalizationinfluenzaintensive care unitmechanical ventilationmedical support

Identifiers

PMID28595669
PMCPMC9148852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.