ArticleAmerican journal of epidemiology2018
Dietary Fat Intake and Fecundability in 2 Preconception Cohort Studies.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 5 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
55 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Do dietary interventions aimed at enhancing fertility improve nutritional status in overweight or obese women?Asia Pacific journal of clinical nutrition · 2025Pooled it
- A Systematic Review of the Effects of High-Fat Diet Exposure on Oocyte and Follicular Quality: A Molecular Point of View.International journal of molecular sciences · 2022Pooled it
- Female dietary patterns and outcomes of in vitro fertilization (IVF): a systematic literature review.Nutrition journal · 2022Pooled it
- Unsaturated Fatty Acid Intake During Periconception and Incidence of Achieving Pregnancy: A Systematic Review and Meta-Analysis.Frontiers in physiology · 2021Pooled it
- Trans Fat Intake and Its Dietary Sources in General Populations Worldwide: A Systematic Review.Nutrients · 2017Pooled it
- Women's health and female fertility: current evidence and knowledge gaps in the Asia-Pacific region.The Lancet regional health. Western Pacific · 2025Review
- Integrative Approaches to Ovulation Induction in Polycystic Ovary Syndrome: A Narrative Review of Conventional and Complementary Therapies.Biomedicines · 2025Review
- Urinary phthalates, serum omega-3 fatty acids and ovarian reserve among women seeking fertility treatment.International journal of hygiene and environmental health · 2025Article
- Relationships between inflammatory indicators, nutritional status, and metabolic status and female infertility.Reproductive health · 2025Article
- Article
- Dietary intake of polyunsaturated fatty acids, their food sources and fertility in females and males: a preconception prospective population-based cohort study.The American journal of clinical nutrition · 2025Article
- All Properties of Infertility Microbiome in a Review Article.Journal of clinical laboratory analysis · 2025Review
- Association between Life's Essential 8 and Infertility as Well as the Mediating Effects of Oxidative Stress and Inflammatory Factors Among U.S. Women Aged 18-45 Years.Reproductive sciences (Thousand Oaks, Calif.) · 2025Article
- Review
- Article
- Association between serum unsaturated fatty acids levels and infertility among American women from the National Health and Nutrition Examination Survey 2013-2014.Lipids in health and disease · 2024Article
- Healthy eating index and risk of diminished ovarian reserve: a case-control study.Scientific reports · 2024Article
- Do Popular Diets Impact Fertility?Nutrients · 2024Review
- Review
- Dietary Patterns and Fertility.Biology · 2024Review
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
The association between dietary fat and fertility is not well studied. We evaluated intakes of total fat, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, trans fatty acids (TFA), ω-3 fatty acids, and ω-6 fatty acids in relation to fecundability in Danish and North American preconception cohort studies. Women who were attempting to become pregnant completed a validated food frequency questionnaire at baseline. Pregnancy status was updated bimonthly for 12 months or until pregnancy. Fecundability ratios (FR) and 95% confidence intervals were estimated using multivariable proportional probabilities regression. Intakes of total fat and saturated, monounsaturated, polyunsaturated, and ω-6 fatty acids were not appreciably associated with fecundability. TFA intake was associated with reduced fecundability in North American women (for the fourth quartile vs. the first, FR = 0.86, 95% confidence interval (CI): 0.71, 1.04) but not Danish women (for the fourth quartile vs. the first, FR = 1.04, 95% CI: 0.86, 1.25), though intake among Danish women was low. In North America, ω-3 fatty acid intake was associated with higher fecundability, but there was no dose-response relationship (among persons who did not use fish oil supplements: for the fourth quartile vs. the first, FR = 1.40, 95% CI: 1.13, 1.73); no association was found in Danish women, among whom low intake was rare. In the present study, high TFA intake and low ω-3 fatty acid intake were associated with reduced fecundity.
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Registered trials
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