ArticlePloS one2017
SbCOMT (Bmr12) is involved in the biosynthesis of tricin-lignin in sorghum.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37 citing papers in PubMed, 93 citations in OpenAlex.
- A NovelPlants (Basel, Switzerland) · 2026Article
- Genome-wide analysis of the R2R3-MYB family reveals potential regulators of lignin and tricin metabolism in the model grass Setaria viridis.Molecular genetics and genomics : MGG · 2026Article
- Brown midrib mutants in sorghum and their applications in renewable energy production.Frontiers in plant science · 2026Review
- Effect of Simulated Gastrointestinal Digestion on the Phenolic Composition and Bioactivity ofFoods (Basel, Switzerland) · 2025Article
- Transcriptomics-proteomics analysis reveals StCOMT1 regulates drought, alkali and combined stresses in potato.Plant cell reports · 2025Article
- Integrative dynamics of cell wall architecture and plant growth under salt stress.Frontiers in plant science · 2025Review
- Comprehensive analysis of the Caffeic acid O-methyltransferase gene family in kenaf (Frontiers in plant science · 2025Article
- Lr34/Yr18/Sr57/Pm38 confers broad-spectrum resistance to fungal diseases via sinapyl alcohol transport for cell wall lignification in wheat.Plant communications · 2024Article
- Engineered reduction of S-adenosylmethionine alters lignin in sorghum.Biotechnology for biofuels and bioproducts · 2024Article
- Decoding the genetic blueprint: regulation of key agricultural traits in sorghum.Advanced biotechnology · 2024Review
- Metabolic engineering ofPlant biotechnology (Tokyo, Japan) · 2024Article
- Simultaneous suppression of lignin, tricin and wall-bound phenolic biosynthesis via the expression of monolignol 4-O-methyltransferases in rice.Plant biotechnology journal · 2024Article
- Genome-wide characterization of COMT family and regulatory role of CsCOMT19 in melatonin synthesis in Camellia sinensis.BMC plant biology · 2024Article
- Grass lignin: biosynthesis, biological roles, and industrial applications.Frontiers in plant science · 2024Review
- Article
- Lignin, the Lignification Process, and Advanced, Lignin-Based Materials.International journal of molecular sciences · 2023Review
- Lignocellulose molecular assembly and deconstruction properties of lignin-altered rice mutants.Plant physiology · 2023Article
- Overexpression of the scopoletin biosynthetic pathway enhances lignocellulosic biomass processing.Science advances · 2022Article
- Deficiency in flavonoid biosynthesis genes CHS, CHI, and CHIL alters rice flavonoid and lignin profiles.Plant physiology · 2022Article
- Spatio-Temporal Modification of Lignin Biosynthesis in Plants: A Promising Strategy for Lignocellulose Improvement and Lignin Valorization.Frontiers in bioengineering and biotechnology · 2022Review
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Authors and funding
13 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lignin in plant biomass represents a target for engineering strategies towards the development of a sustainable bioeconomy. In addition to the conventional lignin monomers, namely p-coumaryl, coniferyl and sinapyl alcohols, tricin has been shown to be part of the native lignin polymer in certain monocot species. Because tricin is considered to initiate the polymerization of lignin chains, elucidating its biosynthesis and mechanism of export to the cell wall constitute novel challenges for the engineering of bioenergy crops. Late steps of tricin biosynthesis require two methylation reactions involving the pathway intermediate selgin. It has recently been demonstrated in rice and maize that caffeate O-methyltransferase (COMT) involved in the synthesis syringyl (S) lignin units derived from sinapyl alcohol also participates in the synthesis of tricin in planta. In this work, we validate in sorghum (Sorghum bicolor L.) that the O-methyltransferase responsible for the production of S lignin units (SbCOMT / Bmr12) is also involved in the synthesis of lignin-linked tricin. In particular, we show that biomass from the sorghum bmr12 mutant contains lower level of tricin incorporated into lignin, and that SbCOMT can methylate the tricin precursors luteolin and selgin. Our genetic and biochemical data point toward a general mechanism whereby COMT is involved in the synthesis of both tricin and S lignin units.
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