Evidence map›Paper›PMID 28594753›Full record

GuidelineObstetrics and gynecology2017

Opioid Use in Pregnancy, Neonatal Abstinence Syndrome, and Childhood Outcomes: Executive Summary of a Joint Workshop by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, American College of Obstetricians and Gynecologists, American Academy of Pediatrics, Society for Maternal-Fetal Medicine, Centers for Disease Control and Prevention, and the March of Dimes Foundation.

Uma M Reddy, Jonathan M Davis, Zhaoxia Ren, Michael F Greene, Opioid Use in Pregnancy, Neonatal Abstinence Syndrome, and Childhood Outcomes Workshop Invited Speakers

Registry-linked trialAbstract readConsensus StatementPractice Guideline
In one paragraph

Guideline in Obstetrics and gynecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04251208 (MOms in REcovery), which is not on this map. Cited by 111 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 4 pooled it
44.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04251208 completednot on this mapstarted 2019, after this paper: background citation

MOms in REcovery (MORE): Defining Optimal Care for Pregnant Women and Infants

TypeobservationalSponsorTrustees of Dartmouth CollegeRan2019 to 2024Enrolled444ConditionsOpioid-Related Disorders, NAS, Substance Use DisordersArmsObservational Study
3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 4 syntheses or guidelines pooled it, 240 citations in OpenAlex.

  1. Guideline
  2. Impact of prenatal opioids on cardiac and autonomic development: systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Pooled it
  3. Maintenance agonist treatments for opiate-dependent pregnant women.The Cochrane database of systematic reviews · 2020
    Pooled it
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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 3 countries.

Uma M ReddyEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, the Tufts University School of Medicine, Boston, Massachusetts, and the Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Jonathan M Davis
Zhaoxia Ren
Michael F Greene
Opioid Use in Pregnancy, Neonatal Abstinence Syndrome, and Childhood Outcomes Workshop Invited Speakers
Asian University for Women · BD

Funding

Establishing Risk in Neonatal Abstinence SyndromeR21DA041706 · NIDA · TUFTS MEDICAL CENTER · PI DAVIS, JONATHAN M., LESTER, BARRY M. · 2016 to 2017
$524k
Intramural NIH HHS Z99 HD999999NIDA NIH HHS R21 DA041706
6 · The paper itself

Abstract

In April 2016, the Eunice Kennedy Shriver National Institute of Child Health and Human Development invited experts to a workshop to address numerous knowledge gaps and to review the evidence for the screening and management of opioid use in pregnancy and neonatal abstinence syndrome. The rising prevalence of opioid use in pregnancy has led to a concomitant dramatic fivefold increase in neonatal abstinence syndrome over the past decade. Experts from diverse disciplines addressed research gaps in the following areas: 1) optimal screening for opioid use in pregnancy; 2) complications of pregnancy associated with opioid use; 3) appropriate treatments for pregnant women with opioid use disorders; 4) the best approaches for detecting, treating, and managing newborns with neonatal abstinence syndrome; and 5) the long-term effects of prenatal opioid exposure on children. Workshop participants identified key scientific opportunities to advance the understanding of opioid use disorders in pregnancy and to improve outcomes for affected women, their children, and their families. This article provides a summary of the workshop presentations and discussions.

Indexed as

ChildChild of Impaired ParentsFemaleHumansInfant, NewbornNeonatal Abstinence SyndromeObstetricsOpioid-Related DisordersPregnancyPregnancy ComplicationsPregnancy OutcomeUnited States

Identifiers

PMID28594753
PMCPMC5486414
OpenAlexW2623927539

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.