Evidence map›Paper›PMID 28593722›Full record

ArticleThe International journal of eating disorders2017

Macronutrient intake associated with weight gain in adolescent girls with anorexia nervosa.

Charumathi Baskaran, Traci L Carson, Karen J Campoverde Reyes, Kendra R Becker, Meghan J Slattery, Shreya Tulsiani, Kamryn T Eddy, Ellen J Anderson, Jane L Hubbard, Madhusmita Misra and 1 more

Open access · greenAbstract read
In one paragraph

Article in The International journal of eating disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Charumathi BaskaranPediatric Endocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0001-6605-8422
Traci L CarsonNeuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.
Karen J Campoverde ReyesPediatric Endocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.
Kendra R BeckerEating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.
Meghan J SlatteryNeuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.
Shreya TulsianiNeuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.
Kamryn T EddyEating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts.
Ellen J AndersonMGH Clinical Research Center, Boston, Massachusetts.
Jane L HubbardMGH Clinical Research Center, Boston, Massachusetts.
Madhusmita MisraPediatric Endocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.
Anne KlibanskiNeuroendocrine Unit, Massachusetts General Hospital, Boston, Massachusetts.
Massachusetts General Hospital · USHarvard University · USMGH Institute of Health Professions · USUniversidade Federal da Paraíba · BR

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
ZD6416 Analgesic--Painful Distal Symmetrical PolyneuropaM01RR001066 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI HOGE, ELIZABETH A · 1985 to 2008
$37.4M
Effects of Anorexia Nervosa on Peak Bone MassR01DK062249 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI KLIBANSKI, ANNE · 2003 to 2015
$7.2M
Bone Metabolism and Body Composition in Young AthletesK24HD071843 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI MISRA, MADHUSMITA · 2013 to 2017
$930k
NCRR NIH HHS M01 RR001066NCRR NIH HHS UL1 RR025758NICHD NIH HHS K24 HD071843NIDDK NIH HHS R01 DK062249
6 · The paper itself

Abstract

objectiveAdolescents and women with anorexia nervosa (AN) are known to severely restrict total calorie and fat intake. However, data are limited regarding specific macronutrient intake associated with weight gain in AN.

objectiveTo prospectively investigate dietary macronutrient composition associated with weight gain in adolescent girls with AN.

methodA prospective naturalistic study of 90 girls 12-18 years old; 45 with AN and 45 healthy normal-weight-controls over a 6-12-month period. Participants completed four-day food diaries and underwent body composition assessment using dual energy X-ray absorptiometry. Weight gain was defined as a ≥10% increase in body mass index (BMI) from baseline.

resultsBaseline clinical characteristics did not differ between girls with AN who did not gain weight (AN-0) versus those who did (AN-1) over the following 6-12 month period except for percentage of calories from proteins (p = 0.046). At 6-12 month follow-up, AN-1 consumed a lower percentage of total calories from protein (p = .001), and a higher percentage of total calories from fat (p = .02) compared to AN-0. AN-1 had a significant increase in the percentage of total calories obtained from and poly-unsaturated-fatty acids (PUFA) (p = 0.006) compared to AN-0, between baseline and follow-up. Within the AN group, BMI at follow-up was associated positively with percentage of total calories obtained from fat, MUFA, and PUFA (p < .05) at 6/12 months, and inversely with the percentage of total calories obtained from carbohydrates and proteins (p = .03). DISCUSSION: Consuming a greater proportion of total calories from fat is associated with weight gain in adolescent girls with AN.

Indexed as

AdolescentAnorexia NervosaChildDietary FatsEnergy IntakeFemaleHumansProspective StudiesWeight GainDietary Fatsanorexia nervosamacronutrient intakeweight gain

Identifiers

PMID28593722
PMCPMC5572315
OpenAlexW2623030532

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.