Evidence map›Paper›PMID 28593524›Full record

Article3 Biotech2017

Virulence factors associated with Coagulase Negative Staphylococci isolated from human infections.

K R Soumya, Suja Philip, Sheela Sugathan, Jyothis Mathew, E K Radhakrishnan

Open access · hybridAbstract read
In one paragraph

Article in 3 Biotech, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Global prevalence of macrolide-resistantFrontiers in microbiology · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Biofilm formation and role of other pathogenic factors in the virulence ofFrontiers in cellular and infection microbiology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Antibiotics (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Molecular Characterizations of the Coagulase-NegativePathogens (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Importance ofThe Journal of international medical research · 2022
    Article
  18. Article
  19. Article
  20. Virulence Factors in Coagulase-Negative Staphylococci.Pathogens (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

K R SoumyaSchool of Biosciences, Mahatma Gandhi University, PD Hills (PO), Kottayam, Kerala, 686 560, India.
Suja PhilipSchool of Biosciences, Mahatma Gandhi University, PD Hills (PO), Kottayam, Kerala, 686 560, India.
Sheela SugathanSree Narayana Institute of Medical Sciences, Chalakka, Ernakulam, Kerala, 683 594, India.
Jyothis MathewSchool of Biosciences, Mahatma Gandhi University, PD Hills (PO), Kottayam, Kerala, 686 560, India.
E K RadhakrishnanSchool of Biosciences, Mahatma Gandhi University, PD Hills (PO), Kottayam, Kerala, 686 560, India. radhakrishnanek@mgu.ac.in.ORCID http://orcid.org/0000-0003-2688-701X
Mahatma Gandhi University · INInstitute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections caused by commensal organisms by changing to infectious life style generate much challenge to the current treatment strategies. Coagulase Negative Staphylococci (CoNS) are one of them, with their coexisting biofilm forming and multiple antibiotic resistance properties form important agents of nosocomial infection. To evaluate species distribution, biofilm formation, and antibiogram, CoNS isolates from various clinical samples were isolated. The presence of biofilm and associated genes icaAB, aap, atlE, embp, bhp, and fbe in CoNS was screened by PCR. The biofilm chemical composition and its correlation with the genotypes were also analysed. Staphylococcus epidermidis (59%) was found to be the most prevalent CoNS species. Most of the CoNS isolates harboring biofilm gene showed carbohydrate-protein-eDNA biofilm, whereas carbohydrate-protein biofilms were also observed. High percentage of multiple drug resistance, and biofilm gene frequency among these CoNS isolates point towards the need of periodic surveillance as CoNS are recently identified to cause difficult to treat infections.

Indexed as

BiofilmBiofilm heterogeneityCoagulase Negative Staphylococciica ADBCica independent genesMethicillin-resistant CoNS

Identifiers

PMID28593524
PMCPMC5462657
OpenAlexW2622715384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.