ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2017
Factors which modulate the rates of skeletal muscle mass loss in non-small cell lung cancer patients: a pilot study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- No evidence for changes in skeletal muscle mass or weight during first-line chemotherapy for metastatic colorectal cancer.BMC cancer · 2019Trial
- A Mathematical Model of the Disruption of Glucose Homeostasis in Cancer Patients.Bulletin of mathematical biology · 2023Article
- Predicting muscle loss during lung cancer treatment (PREDICT): protocol for a mixed methods prospective study.BMJ open · 2021Article
- Loss of skeletal muscle index and survival in patients with metastatic colorectal cancer: Secondary analysis of the phase 3 CAIRO3 trial.Cancer medicine · 2020Article
- Chemotherapy-Induced Sarcopenia.Current treatment options in oncology · 2020Review
- Early Skeletal Muscle Loss in Non-Small Cell Lung Cancer Patients Receiving Chemoradiation and Relationship to Survival.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Factors Contributing to Cancer-Related Muscle Wasting During First-Line Systemic Treatment for Metastatic Colorectal Cancer.JNCI cancer spectrum · 2019Article
- Single-institution study of correlations between skeletal muscle mass, its density, and clinical outcomes in non-small cell lung cancer patients treated with first-line chemotherapy.Thoracic cancer · 2018Article
- Nutritional Status in Patients with Gastrointestinal Cancer in Comparison To Other Cancers In Shiraz, Southern Iran: a Case-Control Study.World journal of plastic surgery · 2018Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAdvanced non-small cell lung cancer (NSCLC) is associated with weight loss which may reflect skeletal muscle mass (SMM) and/or total adipose tissue (TAT) depletion. This study aimed to describe changes in body composition (BC) parameters and to identify the factors unrelated to the tumor which modulate them.
methodsSMM, TAT, and the proportion of SMM to SMM + TAT were assessed with computed tomography. Estimates of each BC parameter at follow-up initiation and across time were derived from a mixed linear model of repeated measurements with a random intercept and a random slope. The same models were used to assess the independent effect of gender, age, body mass index (BMI), and initial values on changes in each BC parameter.
resultsSixty-four patients with stage III or IV NSCLC were reviewed. The mean ± SD decreases in body weight and SMM were respectively 59 ± 3 g/week (P < 0.03) and 7 mm
conclusionOur results demonstrate that SMM wasting in NSCLC is lower when initial SMM and BMI values are low. These exploratory findings after our attempt to better understand the intrinsic factors associated with muscle mass depletion need to be confirmed in larger studies.
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