ArticleProstate international2017
Atherosclerosis is associated with erectile function and lower urinary tract symptoms, especially nocturia, in middle-aged men.
Article in Prostate international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Liver fibrosis is associated with men's health care symptoms, especially erectile dysfunction and lower urinary tract symptoms.Investigative and clinical urology · 2025Article
- The effects of the urotensin-II receptor antagonist palosuran treatment on the corpora cavernosa of streptozotocin-induced diabetic rats.Asian journal of urology · 2025Article
- Associations of cigarette use, e-cigarette use, and dual use, with nocturia and urge urinary incontinence in US adults.Tobacco induced diseases · 2025Article
- Correlations of the Circadian Rhythmicity of Blood Pressure With Erectile Dysfunction.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Nocturia is associated with stiffer central artery and more likely development of major adverse cardiovascular events in men.Frontiers in urology · 2023Article
- International Prostate Symptom Score and Quality of Life Index for Lower Urinary Tract Symptoms Are Associated with Aging Males Symptoms Rating Scale for Late-Onset Hypogonadism Symptoms.The world journal of men's health · 2023Article
- The Etiology and Pathophysiology Genesis of Benign Prostatic Hyperplasia and Prostate Cancer: A New Perspective.Medicines (Basel, Switzerland) · 2021Review
- 3D reconstruction and histopathological analyses on murine corporal body.Reproductive medicine and biology · 2021Article
- Liquid chromatography-mass spectrometry identification of serum biomarkers for nocturia in aged men.World journal of urology · 2019Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtherosclerosis is a systematic disease in which plaque builds up inside the arteries that can lead to serious problems related to quality of life (QOL). Lower urinary tract symptoms (LUTS), erectile dysfunction (ED), and late-onset hypogonadism (LOH) are highly prevalent in aging men and are significantly associated with a reduced QOL. However, few questionnaire-based studies have fully examined the relation between atherosclerosis and several urological symptoms. MATERIALS AND
methodsThe study comprised 303 outpatients who visited our clinic with symptoms of LOH. Several factors influencing atherosclerosis, including serum concentrations of triglyceride, fasting blood sugar, and total testosterone measured by radioimmunoassay, were investigated. We also measured brachial-ankle pulse wave velocity (baPWV) and assessed symptoms by specific questionnaires, including the Sexual Health Inventory for Men (SHIM), Erection Hardness Score (EHS), International Prostate Symptom Score (IPSS), QOL index, and Aging Male Symptoms rating scale (AMS). Stepwise associations between the ratio of measured/age standard baPWV and clinical factors including laboratory data and the scores of the questionnaires were compared using the Jonckheere-Terpstra test for trend. The associations between the ratio of measured/age standard baPWV and each IPSS score were assessed in a multivariate linear regression model after adjustment for serum triglyceride, fasting blood sugar, and total testosterone.
resultsRegarding ED, a higher level of the ratio of measured/age standard baPWV was associated with a lower EHS, whereas no association was found with SHIM. Regarding LUTS, a higher ratio of measured/age standard baPWV was associated with a higher IPSS and QOL index. However, there was no statistically significant difference between the ratio of measured/age standard baPWV and AMS. A multivariate linear regression model showed only nocturia to be associated with the ratio of measured/age standard baPWV for each IPSS score.
conclusionAtherosclerosis is associated with erectile function and LUTS, especially nocturia.
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