ReviewJournal of ultrasound2017
Contrast-enhanced ultrasound of the carotid system: a review of the current literature.
Review in Journal of ultrasound, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05230576 (Deep Learning Model Based on Routine Ultrasound Scanning Video to Help Doctors Improve the Diagnosis of Carotid Plaque), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Deep Learning Model Based on Routine Ultrasound Scanning Video to Help Doctors Improve the Diagnosis of Carotid Plaque
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Duplex ultrasound for diagnosing symptomatic carotid stenosis in the extracranial segments.The Cochrane database of systematic reviews · 2022Pooled it
- Circulating Serum AGRN and ADAMTS8 With Related Candidates as Potential Biomarkers for Carotid Plaque Presence and Vulnerability.CNS neuroscience & therapeutics · 2026Article
- Preliminary study on the use of contrast ultrasound in the preoperative workup of patient-candidates for carotid endarterectomy.Journal of vascular surgery cases and innovative techniques · 2025Article
- Imaging of Carotid Stenosis: Where Are We Standing? Comparison of Multiparametric Ultrasound, CT Angiography, and MRI Angiography, with Recent Developments.Diagnostics (Basel, Switzerland) · 2024Review
- Determinants of Carotid Wall Echolucency in a Cohort of European High Cardiovascular Risk Subjects: A Cross-Sectional Analysis of IMPROVE Baseline Data.Biomedicines · 2024Article
- What Is the Added Value of Carotid CEUS in the Characterization of Atherosclerotic Plaque?Medicina (Kaunas, Lithuania) · 2024Review
- Multiparametric analysis of carotid body tumours: a pictorial essay.Journal of ultrasound · 2023Article
- 3D-Arterial analysis software and CEUS in the assessment of severity and vulnerability of carotid atherosclerotic plaque: a comparison with CTA and histopathology.La Radiologia medica · 2022Article
- [Carotid intraplaque neovascularization is correlated with the risk of revascularization following percutaneous coronary intervention].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022Article
- Synthetic role of miR-200b-3p, ABCDBrain and behavior · 2022Article
- A Review of Clinical Applications for Super-resolution Ultrasound Localization Microscopy.Current medical science · 2022Review
- Application of Model-Building Based on Arterial Ultrasound Imaging Evaluation to Predict CHD Risk.Computational and mathematical methods in medicine · 2022Article
- The Value of Contrast-Enhanced Ultrasound in the Evaluation of Carotid Web.Frontiers in neurology · 2022Article
- Application progress of multiple imaging modalities in Takayasu arteritis.The international journal of cardiovascular imaging · 2021Review
- Ultrasound Methods in the Evaluation of Atherosclerosis: From Pathophysiology to Clinic.Biomedicines · 2021Review
- Feasibility of ex vivo fluorescence imaging of angiogenesis in (non-) culprit human carotid atherosclerotic plaques using bevacizumab-800CW.Scientific reports · 2021Observational
- Usefulness of Carotid Ultrasonography for Risk Stratification of Cerebral and Cardiovascular Disease.Journal of atherosclerosis and thrombosis · 2020Review
- Contrast imaging ultrasound for the detection and characterization of carotid vulnerable plaque.Cardiovascular diagnosis and therapy · 2020Review
- Carotid plaque imaging profiling in subjects with risk factors (diabetes and hypertension).Cardiovascular diagnosis and therapy · 2020Review
- Improved Detection of Molecular Markers of Atherosclerotic Plaques Using Sub-Millimeter PET Imaging.Molecules (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carotid disease is a major current health problem accounting for a significant part of stroke patients. Ultrasound with colour Doppler and spectral analysis is the primary imaging technique used for screening and diagnostic evaluation of the extracranial part of carotid arteries offering identification and grading of carotid disease. However, inherent limitations of this technique include flow-related artefacts like Doppler angle dependence and aliasing artefact which may sometimes hinder complete assessment of a stenotic part of the vessel, potentially failing to address clinically significant differential diagnosis issues. The intravenous use of microbubbles as an US contrast agent has been introduced for the supplementation of conventional technique. The value of contrast-enhanced ultrasound (CEUS) has been investigated in the evaluation of carotid disease leading to promising results. CEUS provides improved flow visualization free of artefacts and detailed plaque surface delineation, thus being able to accurately grade stenosis, identify carotid plaque ulcerations, differentiate occlusion from highly stenotic plaques and identify carotid dissection. Furthermore, microbubbles can be used to identify and grade intraplaque neovascularization, carotid wall inflammation in patients with arteritis, follow-up patients after carotid intervention and assist interventional procedures reducing the need for nephrotoxic contrast agents. The purpose of this review is to present and discuss the current literature regarding the various uses of CEUS in carotid arteries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.