Evidence map›Paper›PMID 28592827›Full record

ArticleScientific reports2017

A comprehensive characterisation of the metabolic profile of varicose veins; implications in elaborating plausible cellular pathways for disease pathogenesis.

Muzaffar A Anwar, Kyrillos N Adesina-Georgiadis, K Spagou, P A Vorkas, J V Li, Joseph Shalhoub, Elaine Holmes, Alun H Davies

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Muzaffar A AnwarAcademic Section of Vascular Surgery, Imperial College, London, UK. m.anwar@imperial.ac.uk.
Kyrillos N Adesina-GeorgiadisAcademic Section of Vascular Surgery, Imperial College, London, UK.
K SpagouDivision of Computational and Systems Medicine, Department of Surgery and Cancer Imperial College, London, UK.
P A VorkasDivision of Computational and Systems Medicine, Department of Surgery and Cancer Imperial College, London, UK.
J V LiDivision of Computational and Systems Medicine, Department of Surgery and Cancer Imperial College, London, UK.
Joseph ShalhoubAcademic Section of Vascular Surgery, Imperial College, London, UK.ORCID 0000-0003-1011-7440
Elaine HolmesDivision of Computational and Systems Medicine, Department of Surgery and Cancer Imperial College, London, UK.
Alun H DaviesAcademic Section of Vascular Surgery, Imperial College, London, UK.
Imperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic phenotypes reflect both the genetic and environmental factors which contribute to the development of varicose veins (VV). This study utilises analytical techniques to provide a comprehensive metabolic picture of VV disease, with the aim of identifying putative cellular pathways of disease pathogenesis. VV (n = 80) and non-VV (n = 35) aqueous and lipid metabolite extracts were analysed using 600 MHz

Indexed as

MetabolomeChromatography, High Pressure LiquidFemaleGene Expression ProfilingHumansMagnetic Resonance SpectroscopyMaleMass SpectrometryRNA, MessengerVaricose VeinsRNA, Messenger

Identifiers

PMID28592827
PMCPMC5462754
OpenAlexW2621192309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.