ArticleJournal of stroke2017
Family History and Stroke Risk in China: Evidence from a Large Cohort Study.
Article in Journal of stroke, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- [Association between different types of first-degree relatives' stroke history and the incidence risk of stroke: A prospective cohort study].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- Family History and ASCVD Risk Among Different Age Groups: Cohort Study in China and the United Kingdom.JACC. Asia · 2026Article
- Family history of stroke - a useful clue for the primary care physician and stroke neurologist: a narrative review.Postepy psychiatrii neurologii · 2023Review
- Demographic characteristics and types of stroke in Southwestern Saudi Arabia, and the potential demand of neuro endovascular specialists.Neurosciences (Riyadh, Saudi Arabia) · 2021Article
- Heritability for stroke: Essential for taking family history.Caspian journal of internal medicine · 2020Review
- The Protective Effects and Mechanisms of Apelin/APJ System on Ischemic Stroke: A Promising Therapeutic Target.Frontiers in neurology · 2020Review
- Validation of 10-Year Stroke Prediction Scores in a Community-Based Cohort of Chinese Older Adults.Frontiers in neurology · 2020Article
- Tea consumption and risk of stroke in Chinese adults: a prospective cohort study of 0.5 million men and women.The American journal of clinical nutrition · 2020Article
- Family History, Tobacco Smoking, and Risk of Ischemic Stroke.Journal of stroke · 2019Article
- Telomere Length: A Potential Biomarker for the Risk and Prognosis of Stroke.Frontiers in neurology · 2019Review
- Knowledge and practices related to stroke prevention among hypertensive and diabetic patients attending Specialist Hospital, Sokoto, Nigeria.The Pan African medical journal · 2018Article
- Interaction Between Methylenetetrahydrofolate Reductase (MTHFR) Gene Polymorphisms and Environment with Susceptibility to Ischemic Stroke in Chinese Population.Annals of Indian Academy of NeurologyArticle
- The Effect of Parental Medical History on the Prevalence of Cerebrovascular Diseases in Their Children in an Iranian Population.Basic and clinical neuroscienceArticle
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
Abstract
background and purposeLarge cohort studies on relationship between family history of stroke (FHS) and stroke risk are lacking in Asians. We aimed to systematically evaluate the association of FHS with stroke risk in a cohort study of 0.5 million Chinese adults.
methodsInformation about FHS was self-reported. The median follow-up time was 7.16 years and the end-point of follow-up was incident stroke, which was entered directly into the China Kadoorie Biobank system. Multivariate analyses were performed with Cox proportional hazards model, and interaction analyses were carried using likelihood-ratio tests.
resultsCompared with participants without FHS, the hazard ratio (HR) (95% confidence interval, CI) of stroke for participants with FHS was 1.50 (1.46-1.55). The HRs increased with the number of first degree relatives with stroke (HRs=1.41, 1.98 and 2.47 for 1, 2 and ≥3 relatives, respectively,
conclusionsFHS is an independent risk factor for stroke in Chinese. The more first degree relatives are affected by stroke, the higher are individuals' risk of suffering from stroke. The management of the health-risk behaviors for reducing stroke should be highlighted, especially for the individuals with FHS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.