ReviewJournal of stroke2017
Blood Pressure Management for Stroke Prevention and in Acute Stroke.
Review in Journal of stroke, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02796664 (Preventive Effects of Ginseng Against Atherosclerosis and Subsequent Ischemic Stroke), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Preventive Effects of Ginseng Against Atherosclerosis and Subsequent Ischemic Stroke: A Randomized Controlled Trial
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quality of stroke guidelines in low- and middle-income countries: a systematic review.Bulletin of the World Health Organization · 2021Pooled it
- Reducing Hypertension in a Poststroke Black and Hispanic Home Care Population: Results of a Pragmatic Randomized Controlled Trial.American journal of hypertension · 2020Trial
- Progress in Synthesis and Pharmacology of Telmisartan.Chemistry & biodiversity · 2026Review
- Projections of the global, regional and national stroke burden by 2050: a systematic analysis for the Global Burden of Disease Study 2021.European journal of epidemiology · 2026Article
- Primary and Secondary Prevention of Ischemic Stroke in Elderly Patients with Cardiovascular Disease: The Role of Frailty and Care Pathways.Neurology international · 2026Review
- Short-duration atrial fibrillation in ischemic stroke: high risk despite subclinical burden-a prospective cohort study.BMC cardiovascular disorders · 2025Article
- [Evaluation of the management of hypertension among stroke patients in a neurology department of Côte d'Ivoire].Medecine tropicale et sante internationale · 2024Article
- 2021 Taiwan Stroke Society Guidelines of blood pressure control for ischemic stroke prevention.Journal of the Chinese Medical Association : JCMA · 2022Article
- Article
- Stroke Risk Factors of Stroke Patients in China: A Nationwide Community-Based Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- Initial in-hospital heart rate is associated with three-month functional outcomes after acute ischemic stroke.BMC neurology · 2021Article
- Cerebral Autoregulation in Ischemic Stroke: From Pathophysiology to Clinical Concepts.Brain sciences · 2021Review
- Impact of aging and comorbidities on ischemic stroke outcomes in preclinical animal models: A translational perspective.Experimental neurology · 2021Review
- Mesenchymal Stem Cell-Based Therapy for Stroke: Current Understanding and Challenges.Frontiers in cellular neuroscience · 2021Review
- Mid to Late Life Hypertension Trends and Cerebral Small Vessel Disease in the Framingham Heart Study.Hypertension (Dallas, Tex. : 1979) · 2020Article
- Effects of fast-track anesthesia on miR-1 and neuropeptides in serum of patients undergoing cardiac surgery.Experimental and therapeutic medicine · 2020Article
- Establishment of Clinical Prediction Model Based on the Study of Risk Factors of Stroke in Patients With Type 2 Diabetes Mellitus.Frontiers in endocrinology · 2020Article
- Role of B1 and B2 lymphocytes in placental ischemia-induced hypertension.American journal of physiology. Heart and circulatory physiology · 2019Article
- Inter-arm Blood Pressure Difference is Associated with Recurrent Stroke in Non-cardioembolic Stroke Patients.Scientific reports · 2019Article
- High-Dose Aspirin Reverses Tartrazine-Induced Cell Growth Dysregulation Independent of p53 Signaling and Antioxidant Mechanisms in Rat Brain.BioMed research international · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elevated blood pressure (BP) is the leading modifiable risk factor for stroke and the benefit of BP lowering therapy on the stroke risk reduction is well established. The optimal BP target for preventing stroke and other vascular events have been controversial, but the evidences from epidemiological studies and randomized controlled trials (RCTs) support intensive BP lowering for greater vascular protection, particularly for stroke prevention. For secondary stroke prevention, the evidence of intensive BP lowering benefit is limited since only a single RCT for patients with lacunar infarctions was conducted and most data were driven by exploratory analyses. In acute intracerebral hemorrhage, immediate BP lowering targeting systolic BP<140 mm Hg is recommended by guidelines based on the results from RCTs. In contrast, in acute ischemic stroke, early BP lowering is not usually recommended because of no benefit on functional outcome and future vascular events and potential harm of stroke progression. This review aims to summarize the updated evidence for optimal BP management for primary and secondary stroke prevention and in patients with acute stroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.