Evidence map›Paper›PMID 28592646›Full record

ArticleG3 (Bethesda, Md.)2017

Loci Contributing to Boric Acid Toxicity in Two Reference Populations of

Michael A Najarro, Jennifer L Hackett, Stuart J Macdonald

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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  9. Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
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  12. The road less traveled: from genotype to phenotype in flies and humans.Mammalian genome : official journal of the International Mammalian Genome Society · 2018
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael A NajarroDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045.
Jennifer L HackettDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045.
Stuart J MacdonaldDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045 sjmac@ku.edu.
University of Kansas · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
A resource for the genetic analysis of complex traitsR01OD010974 · OD · UNIVERSITY OF KANSAS LAWRENCE · PI LONG, ANTHONY DOUGLAS, MACDONALD, STUART JOHN · 2012 to 2019
$3.1M
NIGMS NIH HHS R01 GM084947NIH HHS P40 OD018537NIH HHS R01 OD010974
6 · The paper itself

Abstract

Populations maintain considerable segregating variation in the response to toxic, xenobiotic compounds. To identify variants associated with resistance to boric acid, a commonly-used household insecticide with a poorly understood mechanism of action, we assayed thousands of individuals from hundreds of strains. Using the

Indexed as

Quantitative Trait, HeritableQuantitative Trait LociAnimalsBoric AcidsChromosome MappingDrosophila melanogasterDrug ResistanceGenetics, PopulationGenome-Wide Association StudyInheritance PatternsPharmacogenomic VariantsPhenotypeRNA InterferenceXenobioticsBoric AcidsXenobioticscomplex traitsMPPMulti-parent Advanced Generation Inter-Cross (MAGIC)multiparental populationsquantitative trait lociRNAixenobiotics

Identifiers

PMID28592646
PMCPMC5473745
OpenAlexW2731857052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.