Evidence map›Paper›PMID 28592637›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Bruce A Berkowitz, Jacob Lenning, Nikita Khetarpal, Catherine Tran, Johnny Y Wu, Ali M Berri, Kristin Dernay, E Mark Haacke, Fatema Shafie-Khorassani, Robert H Podolsky and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Stem cell models of Angelman syndrome.Frontiers in cell and developmental biology · 2023
    Review
  3. Neonatal Anesthesia and Oxidative Stress.Antioxidants (Basel, Switzerland) · 2022
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Hippocampal deficits in neurodevelopmental disorders.Neurobiology of learning and memory · 2019
    Review
  19. Article
  20. Oxidative stress measured in vivo without an exogenous contrast agent using QUEST MRI.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Bruce A BerkowitzDepartment of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, USA; baberko@med.wayne.edu.
Jacob LenningDepartment of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Nikita KhetarpalDepartment of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Catherine TranDepartment of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Johnny Y WuDepartment of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Ali M BerriDepartment of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Kristin DernayDepartment of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, USA.
E Mark HaackeDepartment of Radiology, Wayne State University, Detroit, Michigan, USA.
Fatema Shafie-KhorassaniDepartment of Family Medicine and Public Health Sciences, Wayne State University, Detroit, Michigan, USA.
Robert H PodolskyDepartment of Family Medicine and Public Health Sciences, Wayne State University, Detroit, Michigan, USA.
John C GantDepartment of Pharmacology and Nutritional Sciences, University of Kentucky Medical Center, Lexington, Kentucky, USA.
Shaniya MaimaitiDepartment of Pharmacology and Nutritional Sciences, University of Kentucky Medical Center, Lexington, Kentucky, USA.
Olivier ThibaultDepartment of Pharmacology and Nutritional Sciences, University of Kentucky Medical Center, Lexington, Kentucky, USA.
Geoffrey G MurphyDepartment of Molecular and Integrative Physiology, Molecular Behavioral Neuroscience Institute, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Brian M BennettCentre for Neuroscience Studies, Department of Biomedical and Molecular Sciences, Faculty of Health Sciences, Queen's University, Kingston, Ontario, Canada.
Robin RobertsDepartment of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Wayne State University · USUniversity of Kentucky · USQueen's University · CAUniversity of Michigan–Ann Arbor · US

Funding

VISION RESEARCH--COREP30EY004068 · NEI · WAYNE STATE UNIVERSITY · PI LINDA D HAZLETT · 1985 to 2026
$13.2M
Metabolic syndrome and hippocampal Ca2+ dysregulation in aging-related memory decR01AG033649 · NIA · UNIVERSITY OF KENTUCKY · PI THIBAULT, OLIVIER · 2009 to 2019
$3.4M
Novel Imaging Biomarker for Treating Spatial Memory Loss in Prodromal Alzheimer's Disease ModelsR01AG058171 · NIA · WAYNE STATE UNIVERSITY · PI BENNETT, BRIAN M, BERKOWITZ, BRUCE A. · 2017 to 2021
$2.8M
Testing the Calcium Hypothesis of Age-related Cognitive DeclineR01AG052934 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURPHY, GEOFFREY G · 2016 to 2020
$2.1M
Novel Imaging of rod oxidative stress in retinal disease and treatment in vivoR01EY026584 · NEI · WAYNE STATE UNIVERSITY · PI BERKOWITZ, BRUCE A. · 2016 to 2019
$1.5M
L-type Calcium Channels, Neuronal Excitability & Cognition in Aged MiceR01AG028488 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURPHY, GEOFFREY G · 2008 to 2012
$1.5M
Role of calcium channels in the development of diabetic retinopathyR21EY021619 · NEI · WAYNE STATE UNIVERSITY · PI BERKOWITZ, BRUCE A. · 2014 to 2015
$413k
NEI NIH HHS P30 EY004068NEI NIH HHS R01 EY026584NEI NIH HHS R21 EY021619NIA NIH HHS R01 AG028488NIA NIH HHS R01 AG033649NIA NIH HHS R01 AG052934NIA NIH HHS R01 AG058171
6 · The paper itself

Abstract

Hippocampus oxidative stress is considered pathogenic in neurodegenerative diseases, such as Alzheimer disease (AD), and in neurodevelopmental disorders, such as Angelman syndrome (AS). Yet clinical benefits of antioxidant treatment for these diseases remain unclear because conventional imaging methods are unable to guide management of therapies in specific hippocampus subfields

Indexed as

Prodromal SymptomsAldehyde Dehydrogenase, MitochondrialAlzheimer DiseaseAmyloid beta-PeptidesAngelman SyndromeAnimalsAntioxidantsCA1 Region, HippocampalCalciumFree RadicalsMagnetic Resonance ImagingManganeseMemoryMice, KnockoutOxidative StressUbiquitin-Protein LigasesAldehyde Dehydrogenase, MitochondrialALDH2 protein, mouseAmyloid beta-PeptidesAntioxidantsCalciumFree RadicalsManganeseUbe3a protein, mouseUbiquitin-Protein Ligasesdorsoventral CA1MRIneurodegenerative diseaseneurodevelopment disordersreactive oxygen species

Identifiers

PMID28592637
PMCPMC6207301
OpenAlexW2624029039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.