Evidence map›Paper›PMID 28592629›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Immune-Related Tumor Response Dynamics in Melanoma Patients Treated with Pembrolizumab: Identifying Markers for Clinical Outcome and Treatment Decisions.

Mizuki Nishino, Anita Giobbie-Hurder, Michael P Manos, Nancy Bailey, Elizabeth I Buchbinder, Patrick A Ott, Nikhil H Ramaiya, F Stephen Hodi

Abstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Imaging of tumour response to immunotherapy.European radiology experimental · 2020
    Pooled it
  5. Trial
  6. Article
  7. Article
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  9. Article
  10. Article
  11. Doughnut-shaped bone lesions onAnnals of nuclear medicine · 2026
    Article
  12. Article
  13. CAR T-cell therapy induced pseudoprogression.Frontiers in immunology · 2026
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mizuki NishinoDepartment of Radiology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts. Mizuki_Nishino@dfci.harvard.edu.
Anita Giobbie-HurderDepartment of Biostatistics & Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Michael P ManosDepartment of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts.
Nancy BaileyDepartment of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts.
Elizabeth I BuchbinderDepartment of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts.
Patrick A OttDepartment of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts.
Nikhil H RamaiyaDepartment of Radiology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts.
F Stephen HodiDepartment of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts.

Funding

CT Volume Measurement of Lung Cancer treated with Erlotinib: Genomic CorrelationK23CA157631 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI NISHINO, MIZUKI · 2011 to 2015
$902k
NCI NIH HHS K23 CA157631
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overAntibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalBiomarkers, TumorFemaleHumansKaplan-Meier EstimateMaleMelanomaMiddle AgedSkin NeoplasmsTomography, X-Ray ComputedTreatment OutcomeTumor BurdenAntibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalBiomarkers, Tumorpembrolizumab

Identifiers

PMID28592629
PMCPMC5559305

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.