Evidence map›Paper›PMID 28592525›Full record

ArticleDiabetes care2017

Association of Glycemic Status During Progression of Chronic Kidney Disease With Early Dialysis Mortality in Patients With Diabetes.

Connie M Rhee, Csaba P Kovesdy, Vanessa A Ravel, Elani Streja, Steven M Brunelli, Melissa Soohoo, Keiichi Sumida, Miklos Z Molnar, Gregory A Brent, Danh V Nguyen and 1 more

2 registry-linked trialsAbstract read
In one paragraph

Article in Diabetes care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04217161 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Comparison of Dexcom G6 Continuous Glucose Monitoring System and Blood Glucose Levels in Adult Hemodialysis Patients With Diabetes

TypeinterventionalSponsorUniversity of California, IrvineRan2020 to 2023Enrolled30ConditionsDiabetes, Hemodialysis, Glucose MeasurementArmsDexcom G6 Continuous Glucose Monitor
NCT05509881 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Continuous Glucose Monitoring in Dialysis Patients to Overcome Dysglycemia Trial

TypeinterventionalSponsorUniversity of California, IrvineRan2023 to 2026Enrolled122ConditionsHemodialysis, Diabete Mellitus, Continuous Glucose MonitoringArmsContinuous glucose monitoring (CGM), Usual care (Self-monitored blood glucose)
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  17. Race and Mortality in CKD and Dialysis: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Connie M RheeHarold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine School of Medicine, Orange, CA kkz@uci.edu crhee1@uci.edu.
Csaba P KovesdyDivision of Nephrology, University of Tennessee Health Science Center, Memphis, TN.
Vanessa A RavelHarold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine School of Medicine, Orange, CA.
Elani StrejaHarold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine School of Medicine, Orange, CA.
Steven M BrunelliDaVita Clinical Research, Minneapolis, MN.
Melissa SoohooHarold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine School of Medicine, Orange, CA.
Keiichi SumidaDivision of Nephrology, University of Tennessee Health Science Center, Memphis, TN.
Miklos Z MolnarDivision of Nephrology, University of Tennessee Health Science Center, Memphis, TN.
Gregory A BrentDivision of Endocrinology, Diabetes and Hypertension, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Danh V NguyenDivision of General Internal Medicine, University of California Irvine, Orange, CA.
Kamyar Kalantar-ZadehHarold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine School of Medicine, Orange, CA kkz@uci.edu crhee1@uci.edu.ORCID 0000-0002-8666-0725

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
Multilevel Time-Dynamic Modeling of Hospitalization and Survival in Patients on DialysisR01DK092232 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KURUM, ESRA, NGUYEN, DANH V · 2011 to 2025
$4.9M
Transition of Care in CKD (TC-CKD)U01DK102163 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI JACOBSEN, STEVEN J, KALANTAR-ZADEH, KAMYAR · 2014 to 2018
$2.8M
MALNUTRITION, DIET AND RACIAL DISPARITIES IN CKDK24DK091419 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI KALANTAR-ZADEH, KAMYAR · 2011 to 2020
$1.8M
Hypothyroidism, Cardiovascular Health, and Survival in Kidney DiseaseK23DK102903 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI RHEE, CONNIE MEEYOUNG · 2014 to 2018
$955k
Racial and Cardiovascular Risk Factor Anomalies in CKDR01DK096920 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI KALANTAR-ZADEH, KAMYAR, KOVESDY, CSABA PAL · 2013 to 2015
$909k
Improving Analysis of Endogenous Multimodal Treatments for Use in Geriatrics Health Outcomes StudiesI01HX002237 · VA · VA BOSTON HEALTH CARE SYSTEM · PI GARRIDO, MELISSA M · 2018 to 2021
–
Lipid Profiles and Management in Veterans with Chronic Kidney DiseaseIK2CX001266 · VA · VETERANS HEALTH ADMINISTRATION · PI STREJA, ELANI · 2016 to 2021
–
CSRD VA IK2 CX001266HSRD VA SDR 02-237NCATS NIH HHS UL1 TR001414NIDDK NIH HHS K23 DK102903NIDDK NIH HHS K24 DK091419NIDDK NIH HHS R01 DK092232NIDDK NIH HHS R01 DK096920NIDDK NIH HHS U01 DK102163
6 · The paper itself

Abstract

objectiveAlthough early trials suggested that intensive glycemic targets reduce the number of complications with diabetes, contemporary trials indicate no cardiovascular benefit and potentially higher mortality risk. As patients with advanced chronic kidney disease (CKD) transitioning to treatment with dialysis were excluded from these studies, the optimal glycemic level in this population remains uncertain. We hypothesized that glycemic status, defined by hemoglobin A RESEARCH DESIGN AND

methodsAmong 17,819 U.S. veterans with diabetic CKD transitioning to dialysis from October 2007 to September 2011, we examined the association of mean HbA--

resultsHbA--

conclusionsIn patients with diabetes and CKD transitioning to dialysis, higher mean HbA--

Indexed as

AgedAged, 80 and overBlood GlucoseDiabetic NephropathiesDisease ProgressionFemaleGlycated HemoglobinHumansIncidenceLongitudinal StudiesMaleMiddle AgedRenal DialysisRenal Insufficiency, ChronicSocioeconomic FactorsUnited StatesBlood GlucoseGlycated Hemoglobin

Identifiers

PMID28592525
PMCPMC5521972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.