Evidence map›Paper›PMID 28592453›Full record

ReviewNeurology2017

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.

Ian G McKeith, Bradley F Boeve, Dennis W Dickson, Glenda Halliday, John-Paul Taylor, Daniel Weintraub, Dag Aarsland, James Galvin, Johannes Attems, Clive G Ballard and 53 more

9 registry-linked trialsOpen access · bronzeAbstract readReviewConsensus Statement
In one paragraph

Review in Neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 2,267 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,267citing papers in PubMed, 2 pooled it
203.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03594851 nacompletednot on this mapstarted 2018, after this paper: background citation

Evaluation of the Benefits of Individualized Advice Administration on Quality of Sleep for the Elderly Living at Home Prospective, Monocentric and Open Study

TypeinterventionalSponsorGroupe Hospitalier de la Region de Mulhouse et Sud AlsaceRan2018 to 2019Enrolled45ConditionsSleep Disorder, Complaint, Subjective HealthArmsPittsburgh Sleep Quality Index, Sleep diary, Katz Index of Independence in Activities of Daily Living, Lawton Instrumental Activities of Daily Living, Neuropsychiatric Inventory (Cummings)
NCT05150158 unknown statusnot on this mapstarted 2021, after this paper: background citation

New Biomarkers in Parkinson's Disease

TypeobservationalSponsorNeuromed IRCCSRan2021 to 2022Enrolled60ConditionsParkinson Disease
NCT05188105 nacompletednot on this mapstarted 2021, after this paper: background citation

Interventional Cross-over Study to Evaluate the Efficacy of Transcranial Alternating Current Stimulation (tACS) on Cognitive Performance in Patients With Dementia With Lewy Bodies

TypeinterventionalSponsorAzienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaRan2021 to 2024Enrolled15ConditionsDementia With Lewy Bodies, Lewy Body DiseaseArmsAlpha tACS (12 Hz) over the occipital cortex
NCT06357195 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Implementation of DIAMOND-Lewy Guidelines for Emergency Department Antipsychotic Use in Older Patients With Cognitive and Movement Disorders

TypeobservationalSponsorOhio State UniversityRan2024 to 2026Enrolled1,000ConditionsEmergency Psychiatric, Cognition Disorder, Movement Disorders, Antipsychotics and Neuroleptics Toxicity
NCT06826157 naenrolling by invitationnot on this mapstarted 2021, after this paper: background citation

Assessing the Role of Advanced Electroencephalographic Data as Marker of Pathology and Prognosis in Primary Dementias

TypeinterventionalSponsorIRCCS San RaffaeleRan2021 to 2027Enrolled175ConditionsAlzheimer Disease, Lewy Body Dementia (LBD), Mild Alzheimer Disease, Frontotemporal Dementia (FTD)ArmsElectroencephalogram, 3 Tesla MRI, Apolipoprotein E genetic test
NCT06961760 no longer availablenot on this map

A Single-arm, Open-label, Expanded Access Program to Provide 100 mg CT1812 (Zervimesine) and to Collect Long-term Safety and Efficacy Data in Participants With Mild-to-moderate Dementia With Lewy Bodies (DLB).

Typeexpanded_accessSponsorCognition TherapeuticsConditionsDementia With Lewy BodiesArmszervimesine
NCT07375771 narecruitingnot on this mapstarted 2025, after this paper: background citation

Interventional Study to Evaluate the Effectiveness of Transcranial Alternating Current Stimulation (tACS) on Cognitive Performance in Patients With Lewy Body Dementia

TypeinterventionalSponsorIRCCS Centro San Giovanni di Dio FatebenefratelliRan2025 to 2030Enrolled40ConditionsLewy Body Dementia (LBD), Transcranial Alternating Current StimulationArmsTranscranial Alternating Current Stimulation, Sham Transcranial Alternating Current Stimulation
NCT07629349 recruitingnot on this mapstarted 2020, after this paper: background citation

Dementia With Lewy Bodies: Clinical Symptoms, Biomarkers and Progression

TypeobservationalSponsorKarolinska InstitutetRan2020 to 2031Enrolled600ConditionsDementia With Lewy Bodies (DLB), Mild Cognitive Impairment (MCI), Cognitively Unimpaired, Other Dementias
NCT07731191 narecruitingnot on this mapstarted 2026, after this paper: background citation

Development of Digital Solutions for the Prediction of the Biological Mechanisms of Alzheimer's Disease Through the Analysis of Risk Factors (PrevAI)

TypeinterventionalSponsorIRCCS Centro San Giovanni di Dio FatebenefratelliRan2026 to 2026Enrolled240ConditionsMild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)ArmsDigital solution for the prediction of the biological mechanisms of Alzheimer's disease through the analysis of risk factors
3 · Its place in the literature

Who cites it

2,267 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4,305 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  17. [Dementia with Lewy bodies].Fortschritte der Neurologie-Psychiatrie · 2026
    Review
  18. E326KJournal of Parkinson's disease · 2026
    Article
  19. Gray Matter Microstructure Measured Using Diffusion Imaging as a Biomarker of Severity in Lewy Body Diseases.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  20. Article

2,207 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

63 authors at 1 institution in 1 country.

Ian G McKeithAuthor affiliations are provided at the end of the article. ian.mckeith@newcastle.ac.uk.
Bradley F BoeveAuthor affiliations are provided at the end of the article.
Dennis W DicksonAuthor affiliations are provided at the end of the article.
Glenda HallidayAuthor affiliations are provided at the end of the article.
John-Paul TaylorAuthor affiliations are provided at the end of the article.
Daniel WeintraubAuthor affiliations are provided at the end of the article.
Dag AarslandAuthor affiliations are provided at the end of the article.
James GalvinAuthor affiliations are provided at the end of the article.
Johannes AttemsAuthor affiliations are provided at the end of the article.
Clive G BallardAuthor affiliations are provided at the end of the article.
Ashley BaystonAuthor affiliations are provided at the end of the article.
Thomas G BeachAuthor affiliations are provided at the end of the article.
Frédéric BlancAuthor affiliations are provided at the end of the article.
Nicolaas BohnenAuthor affiliations are provided at the end of the article.
Laura BonanniAuthor affiliations are provided at the end of the article.
Jose BrasAuthor affiliations are provided at the end of the article.
Patrik BrundinAuthor affiliations are provided at the end of the article.
David BurnAuthor affiliations are provided at the end of the article.
Alice Chen-PlotkinAuthor affiliations are provided at the end of the article.
John E DudaAuthor affiliations are provided at the end of the article.
Omar El-AgnafAuthor affiliations are provided at the end of the article.
Howard FeldmanAuthor affiliations are provided at the end of the article.
Tanis J FermanAuthor affiliations are provided at the end of the article.
Dominic FfytcheAuthor affiliations are provided at the end of the article.
Hiroshige FujishiroAuthor affiliations are provided at the end of the article.
Douglas GalaskoAuthor affiliations are provided at the end of the article.
Jennifer G GoldmanAuthor affiliations are provided at the end of the article.
Stephen N GompertsAuthor affiliations are provided at the end of the article.
Neill R Graff-RadfordAuthor affiliations are provided at the end of the article.
Lawrence S HonigAuthor affiliations are provided at the end of the article.
Alex IranzoAuthor affiliations are provided at the end of the article.
Kejal KantarciAuthor affiliations are provided at the end of the article.
Daniel KauferAuthor affiliations are provided at the end of the article.
Walter KukullAuthor affiliations are provided at the end of the article.
Virginia M Y LeeAuthor affiliations are provided at the end of the article.
James B LeverenzAuthor affiliations are provided at the end of the article.
Simon LewisAuthor affiliations are provided at the end of the article.
Carol LippaAuthor affiliations are provided at the end of the article.
Angela LundeAuthor affiliations are provided at the end of the article.
Mario MasellisAuthor affiliations are provided at the end of the article.
Eliezer MasliahAuthor affiliations are provided at the end of the article.
Pamela McLeanAuthor affiliations are provided at the end of the article.
Brit MollenhauerAuthor affiliations are provided at the end of the article.
Thomas J MontineAuthor affiliations are provided at the end of the article.
Emilio MorenoAuthor affiliations are provided at the end of the article.
Etsuro MoriAuthor affiliations are provided at the end of the article.
Melissa MurrayAuthor affiliations are provided at the end of the article.
John T O'BrienAuthor affiliations are provided at the end of the article.
Sotoshi OrimoAuthor affiliations are provided at the end of the article.
Ronald B PostumaAuthor affiliations are provided at the end of the article.
Shankar RamaswamyAuthor affiliations are provided at the end of the article.
Owen A RossAuthor affiliations are provided at the end of the article.
David P SalmonAuthor affiliations are provided at the end of the article.
Andrew SingletonAuthor affiliations are provided at the end of the article.
Angela TaylorAuthor affiliations are provided at the end of the article.
Alan ThomasAuthor affiliations are provided at the end of the article.
Pietro TiraboschiAuthor affiliations are provided at the end of the article.
Jon B ToledoAuthor affiliations are provided at the end of the article.
John Q TrojanowskiAuthor affiliations are provided at the end of the article.
Debby TsuangAuthor affiliations are provided at the end of the article.
Zuzana WalkerAuthor affiliations are provided at the end of the article.
Masahito YamadaAuthor affiliations are provided at the end of the article.
Kenji KosakaAuthor affiliations are provided at the end of the article.
School of the Art Institute of Chicago · US

Funding

Vascular Structure and Function in Cognitive AgingP01AG003949 · NIA · YESHIVA UNIVERSITY · PI Charles B Hall · 1985 to 2026
$73.9M
NATIONAL ALZHEIMERS COORDINATING CENTER (NACC)U01AG016976 · NIA · UNIVERSITY OF WASHINGTON · PI KUKULL, WALTER ANTHONY · 1999 to 2020
$72.8M
THERAPEUTIC EFFECTS OF INTRA-NASAL INSULIN DETEMIRP50AG005136 · NIA · UNIVERSITY OF WASHINGTON · PI GRABOWSKI, THOMAS J. · 1985 to 2019
$57.2M
VIRUS-INDUCED BRAIN PATHOLOGYP50AG005131 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BREWER, JAMES B · 1985 to 2018
$55.4M
THE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI PETERSEN, RONALD C · 1999 to 2018
$36.9M
UPenn ADCC Biomarker CoreP30AG010124 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DETRE, JOHN A · 1991 to 2020
$35.1M
Project IV: "Alpha-Synuclein Strains & Diverse Synucleinopathies"P50NS053488 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI TROJANOWSKI, JOHN Q. · 2007 to 2017
$20.9M
Public Outreach and Education CoreP50NS091856 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2014 to 2019
$10.1M
Neuropathology CoreP50NS072187 · NINDS · MAYO CLINIC JACKSONVILLE · PI DICKSON, DENNIS WILLIAM · 2010 to 2017
$8.7M
Genetic Analysis Of Non- Alzheimer's disease DementiasZIAAG000951 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW · 2009 to 2020
$5.6M
TMEM106B in neurodegenerative diseaseR01NS082265 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI CHEN-PLOTKIN, ALICE S · 2013 to 2024
$4.7M
Neuroimmune responses and therapeutics of alpha-synucleinopathies of the aging populationZIAAG000936 · NIA · NATIONAL INSTITUTE ON AGING · PI COOKSON, MARK · 2017 to 2025
$4.1M
Medical Research Council G0400074Medical Research Council G0502157Medical Research Council G0900652Medical Research Council G1100540NIA NIH HHS P01 AG003949NIA NIH HHS P30 AG010124NIA NIH HHS P50 AG005131NIA NIH HHS P50 AG005136NIA NIH HHS P50 AG016574NIA NIH HHS U01 AG016976NINDS NIH HHS P50 NS053488NINDS NIH HHS P50 NS072187NINDS NIH HHS P50 NS091856NINDS NIH HHS R01 NS078086NINDS NIH HHS R01 NS082265NINDS NIH HHS R13 NS095618NINDS NIH HHS U01 NS082134NINDS NIH HHS U01 NS097056
6 · The paper itself

Abstract

The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous report, which has been in widespread use for the last decade. The revised DLB consensus criteria now distinguish clearly between clinical features and diagnostic biomarkers, and give guidance about optimal methods to establish and interpret these. Substantial new information has been incorporated about previously reported aspects of DLB, with increased diagnostic weighting given to REM sleep behavior disorder and

Indexed as

BiomarkersPractice Guidelines as TopicHumansLewy Body DiseaseBiomarkers

Identifiers

PMID28592453
PMCPMC5496518
OpenAlexW2623521763

What OpenQuestion holds

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Read underepoch 390

Registered trials

and 3 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.