ArticleBMC nephrology2017
White blood cell count predicts the odds of kidney function decline in a Chinese community-based population.
Article in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 39 citations in OpenAlex.
- Novel urinary glycan profiling by lectin array serves as the biomarkers for predicting renal prognosis in patients with IgA nephropathy.Scientific reports · 2021Trial
- Chronic Kidney Disease Severity Is Associated With Selective Expansion of a Distinctive Intermediate Monocyte Subpopulation.Frontiers in immunology · 2018Trial
- Predicting future kidney function in type 2 diabetes mellitus using machine learning and baseline health information.Scientific reports · 2026Article
- Association Between the Modified Furosemide Response Index and Prognosis in Patients with Chronic Kidney Disease: A Retrospective Cohort Study Based on the MIMIC-IV Database.International journal of nephrology and renovascular disease · 2026Article
- MDCT-based Grading of Perirenal Changes Secondary to Acute Unilateral Upper Urinary Tract Obstruction.Current medical imaging · 2025Article
- Therapeutic potential of L-Carnitine in improving adenine-induced hematological abnormalities in rats: A preclinical pharmacological study.Open veterinary journal · 2025Article
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- The possible role of the vasopressin system in hematopoiesis.Scientific reports · 2024Article
- A link between white blood cell count and blood pressure levels.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Systemic Immune Inflammation Index as a Key Predictor of Dialysis in Pediatric Chronic Kidney Disease with the Use of Random Forest Classifier.Journal of clinical medicine · 2023Article
- Evaluation of Bcl-2 as a marker for chronic kidney disease prediction in cats.Frontiers in veterinary science · 2022Article
- Associations between remnant lipoprotein cholesterol and central systolic blood pressure in a Chinese community-based population: a cross-sectional study.Lipids in health and disease · 2021Article
- Presepsin in the Rapid Response System for Cancer Patients: A Retrospective Analysis.Journal of clinical medicine · 2021Article
- The relationship between neutrophil-lymphocyte ratio and early renal fibrosis and renal prognosis in patients with lupus nephritis.American journal of translational research · 2021Article
- Remdesivir, Renal Function and Short-Term Clinical Outcomes in Elderly COVID-19 Pneumonia Patients: A Single-Centre Study.Clinical interventions in aging · 2021Observational
- Relationship between lactate dehydrogenase and albuminuria in Chinese hypertensive patients.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Article
- RGS5 plays a significant role in renal cell carcinoma.Royal Society open science · 2020Article
- From Local Explanations to Global Understanding with Explainable AI for Trees.Nature machine intelligence · 2020Article
- Predictive value of serum albumin-to-globulin ratio for incident chronic kidney disease: A 12-year community-based prospective study.PloS one · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInflammatory processes are very important in the development of kidney disease. Nevertheless, the association between white blood cell (WBC) count and the risk of renal dysfunction has not been well-established, especially in subjects without chronic kidney disease (CKD). Our study investigated the association between WBC count and kidney function decline in a Chinese community-based population with baseline estimated glomerular filtration rate (eGFR) ≥60 mL/min/1.73 m
methodsA total of 3768 subjects who were enrolled in an atherosclerosis cohort in Beijing were included in this study. EGFRs were calculated at baseline and follow-up using the CKD-EPI formula. The outcomes of this study were renal function decline (RFD) (a drop in eGFR stage along with a decline in eGFR of 25% or exceeding 5 mL/min/1.73 m
resultsOn average, the subjects were 56.6 ± 8.5 years old, and 35.9% were male. Of the participants, 48.6% had hypertension and 17.4% had diabetes. The mean (SD) WBC count at baseline was 6.1 ± 1.5 × 10
conclusionsIn conclusion, elevated WBC count served as a predictor of the odds of kidney function decline in this population, which supports the hypothesis that systemic inflammation may serve as a risk factor for CKD development.
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