Evidence map›Paper›PMID 28592227›Full record

SynthesisBMC cardiovascular disorders2017

Long-term outcome of bioresorbable vascular scaffolds for the treatment of coronary artery disease: a meta-analysis of RCTs.

Alberto Polimeni, Remzi Anadol, Thomas Münzel, Ciro Indolfi, Salvatore De Rosa, Tommaso Gori

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Observational
  6. Review
  7. Article
  8. Coronary Stent Thrombosis- Predictors and Prevention.Deutsches Arzteblatt international · 2020
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Bioresorbable vascular scaffold: a step back thinking of the future.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2018
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alberto PolimeniZentrum für Kardiologie, University Hospital Mainz, Mainz, Germany.ORCID 0000-0002-9166-3031
Remzi AnadolZentrum für Kardiologie, University Hospital Mainz, Mainz, Germany.
Thomas MünzelZentrum für Kardiologie, University Hospital Mainz, Mainz, Germany.
Ciro IndolfiDivision of Cardiology, Department of Medical and Surgical Sciences, "Magna Graecia" University, 88100, Catanzaro, Italy.
Salvatore De RosaDivision of Cardiology, Department of Medical and Surgical Sciences, "Magna Graecia" University, 88100, Catanzaro, Italy.
Tommaso GoriZentrum für Kardiologie, University Hospital Mainz, Mainz, Germany. tommaso.gori@unimedizin-mainz.de.
Johannes Gutenberg University Mainz · DEMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary bioresorbable scaffolds (BRS) were developed to overcome the limitations of standard metallic stents, especially to address late events after percutaneous coronary interventions. The aim of this meta-analysis was to evaluate the efficacy and safety of BRS, compared with Everolimus-eluting stents (EES), using the data available from randomized trials, with a focus on long-term outcomes.

methodsPublished randomized trials comparing BRS to EES for the treatment of coronary artery disease were searched for within PubMed, Cochrane Library and Scopus electronic databases up to April 4th 2017. The summary measure used was odds ratio (OR) with 95% confidence intervals.

resultsA total of 5 studies were eligible, including 5219 patients. At 2 years, BRS was associated with higher rates of target lesion failure (9.4% vs 7.2%; OR = 1.33; 95% CI 1.07 to 1.63; p = 0.008) and device thrombosis (2.3% vs 0.7%; OR = 3.22; 95% CI 1.86 to 5.57; p < 0.0001) compared with EES. The incidence of both early (within 30 days after implantation, 1.1% vs 0.5%, OR 1.97, 95% CI 1.02 to 3.81; p = 0.05) and very-late device thrombosis (>1 year, 0.6% vs 0.1%, OR 4.03, 95% CI 1.37 to 11.82; p = 0.01) was higher with BRS compared with EES.

conclusionsBRS may be associated with worse two-years clinical outcomes compared with EES in patients with coronary artery disease.

Indexed as

Absorbable ImplantsDrug-Eluting StentsCardiovascular AgentsChi-Square DistributionCoronary Artery DiseaseCoronary ThrombosisEverolimusHumansOdds RatioPercutaneous Coronary InterventionProsthesis DesignRandomized Controlled Trials as TopicRisk FactorsTime FactorsTreatment OutcomeCardiovascular AgentsEverolimusBioresorbable vascular scaffoldStent thrombosisTarget lesion failure

Identifiers

PMID28592227
PMCPMC5463321
OpenAlexW2621966827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.