ArticleAmerican journal of epidemiology2017
Prospective Cohort Study of Uterine Fibroids and Miscarriage Risk.
Article in American journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- The Annual Economic Burden of Uterine Fibroids in the United States (2010 Versus 2022): A Comparative Cost-Analysis.Reproductive sciences (Thousand Oaks, Calif.) · 2024Pooled it
- Leiomyomas in Pregnancy and Spontaneous Abortion: A Systematic Review and Meta-analysis.Obstetrics and gynecology · 2017Pooled it
- Fibroids and health disparities: the COllaboration for EQuity in Uterine Leiomyomas specialized center.American journal of obstetrics and gynecology · 2026Article
- Physician Management of Non-Cavity Distorting Intramural Fibroids and Infertility: A Survey of REI Providers.International journal of women's health · 2026Article
- Influence of uterine fibroid size on perinatal and neonatal outcomes: a single-centre cohort of 651 pregnancies.BMC pediatrics · 2025Article
- Removal of FIGO V and VI fibroids with a combined size greater than 5 cm quadruples spontaneous fecundity relative to myomectomy for those with smaller fibroids.Archives of gynecology and obstetrics · 2025Article
- Uterine artery doppler and pregnancy-associated plasma protein-A in pregnancies with fibroids.Clinics (Sao Paulo, Brazil) · 2025Article
- Uterine fibroids and Black people of African descent globally: a scoping review protocol.BMJ open · 2024Article
- Molecular examination for Coxiella burnetii and Brucella spp. infections in Iranian women experiencing spontaneous miscarriage.BMC infectious diseases · 2024Article
- First-Trimester Screening for Miscarriage or Stillbirth-Prediction Model Based on MicroRNA Biomarkers.International journal of molecular sciences · 2023Article
- Periconceptional folic acid supplementation and child asthma: aThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2022Article
- Uterine Fibroids and Pregnancy: How Do They Affect Each Other?Reproductive sciences (Thousand Oaks, Calif.) · 2022Review
- Uterine fibroids increase the risk of preterm birth and other adverse birth events: a systematic review and meta-analysis.Translational pediatrics · 2022Article
- Uterine Fibroids and Pregnancy: A Review of the Challenges from a Romanian Tertiary Level Institution.Healthcare (Basel, Switzerland) · 2022Article
- Route of myomectomy and fertility: a prospective cohort study.Fertility and sterility · 2022Article
- Uterine fibroids and risk of preterm birth by clinical subtypes: a prospective cohort study.BMC pregnancy and childbirth · 2021Article
- Laparoscopic Intracapsular Myomectomy in Women 40 Years Old and Over with Symptomatic Uterine Fibroids. A Pilot Study.Surgery journal (New York, N.Y.) · 2021Article
- Association of uterine fibroids with birthweight and gestational age.Annals of epidemiology · 2020Article
- Article
- Moving Toward Individualized Medicine for Uterine Leiomyomas.Obstetrics and gynecology · 2018Article
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7 authors.
Funding
Abstract
We sought to determine the relationship of fibroids to pregnancy loss in a prospective cohort in which fibroid status was uniformly documented in early pregnancy. Participants had an intake interview, transvaginal ultrasonography, computer-assisted telephone interview, and follow-up assessment of outcomes. We recruited diverse participants for the Right From the Start study from 8 metropolitan areas in 3 states in the United States during 2000-2012. Participants were at least 18 years of age, trying to become pregnant or at less than 12 weeks' gestation, not using fertility treatments, fluent in English or Spanish, and available for telephone interviews. Miscarriage was defined as loss before 20 weeks' gestation. Fibroid presence, number, type, and volume were assessed using standardized ultrasonography methods. We used proportional hazards models to estimate associations. Among 5,512 participants, 10.4% had at least 1 fibroid, and 10.8% experienced a miscarriage. Twenty-three percent had experienced a prior miscarriage and 52% prior births. Presence of fibroids was associated with miscarriage in models without adjustments. Adjusting for key confounders indicated no increase in risk (adjusted hazard ratio = 0.83, 95% confidence interval: 0.63, 1.08). No characteristic of fibroids was associated with risk. Prior evidence attributing miscarriage to fibroids is potentially biased. These findings imply that surgical removal of fibroids to reduce risk of miscarriage deserves careful scrutiny.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.