Evidence map›Paper›PMID 28591681›Full record

ReviewCurrent opinion in structural biology2017

Structural features of glycan recognition among viral pathogens.

Sreejesh Shanker, Liya Hu, Sasirekha Ramani, Robert L Atmar, Mary K Estes, B V Venkataram Prasad

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in structural biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. The Crossroads between Host Copper Metabolism and Influenza Infection.International journal of molecular sciences · 2021
    Review
  4. Article
  5. Synthetic Carbohydrate Chemistry and Translational Medicine.The Journal of organic chemistry · 2020
    Article
  6. Backbone Free Energy Estimator Applied to Viral Glycoproteins.Journal of computational biology : a journal of computational molecular cell biology · 2020
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Human vaccines & immunotherapeutics · 2019
    Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sreejesh ShankerVerna and Marrs McLean Department of Biochemistry and Molecular Biology. Electronic address: shanker@bcm.edu.
Liya HuVerna and Marrs McLean Department of Biochemistry and Molecular Biology.
Sasirekha RamaniDepartment of Molecular Virology and Microbiology.
Robert L AtmarDepartment of Molecular Virology and Microbiology; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, United States.
Mary K EstesDepartment of Molecular Virology and Microbiology; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, United States.
B V Venkataram PrasadVerna and Marrs McLean Department of Biochemistry and Molecular Biology. Electronic address: vprasad@bcm.edu.
Baylor College of Medicine · US

Funding

X-ray Crystallographic Studies on CalicivirusesP01AI057788 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI PRASAD, BIDADI VENKATARAM · 2004 to 2024
$34.4M
Structural Studies on RotavirusesR37AI036040 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI PRASAD, BIDADI VENKATARAM · 2003 to 2022
$10.9M
Regulation of Rotavirus ReplicationR01AI080656 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI Sue Ellen Crawford, Mary Kolb Estes · 2009 to 2026
$7.9M
Intestinal and Milk Glycan Expression in Restriction of Neonatal InfectionR01AI105101 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI ESTES, MARY KOLB · 2013 to 2016
$1.5M
NIAID NIH HHS P01 AI057788NIAID NIH HHS R01 AI080656NIAID NIH HHS R01 AI105101NIAID NIH HHS R37 AI036040
6 · The paper itself

Abstract

Recognition and binding to host glycans present on cellular surfaces is an initial and critical step in viral entry. Diverse families of host glycans such as histo-blood group antigens, sialoglycans and glycosaminoglycans are recognized by viruses. Glycan binding determines virus-host specificity, tissue tropism, pathogenesis and potential for interspecies transmission. Viruses including noroviruses, rotaviruses, enteroviruses, influenza, and papillomaviruses have evolved novel strategies to bind specific glycans often in a strain-specific manner. Structural studies have been instrumental in elucidating the molecular determinants of these virus-glycan interactions, aiding in developing vaccines and antivirals targeting this key interaction. Our review focuses on these key structural aspects of virus-glycan interactions, particularly highlighting the different strain-specific strategies employed by viruses to bind host glycans.

Indexed as

Host-Pathogen InteractionsVirus Physiological PhenomenaAnimalsHumansPolysaccharidesVirusesPolysaccharides

Identifiers

PMID28591681
PMCPMC5733725
OpenAlexW2620955321

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.