ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2017
Oral Candida spp carriage and periodontal diseases in HIV-infected patients in Ribeirão Preto, Brazil.
Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03262402 (Determination of Factors Involved in the Pathogenesis of Periodontal Diseases in HIV-infected Patients), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Determination of Factors Involved in the Pathogenesis of Periodontal Diseases in HIV-infected Patients
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of probiotics for oral candidiasis management: a systematic review.BMC oral health · 2025Pooled it
- Distribution ofHealthcare (Basel, Switzerland) · 2026Review
- Assessing the vulnerability of Candida colonization through social determinants of health among college students in Puebla, Mexico.Journal of health, population, and nutrition · 2025Article
- Subgingival biofilm colonization by Candida albicans and Candida dubliniensis in patients living with HIV from Buenos Aires, Argentina.Acta odontologica latinoamericana : AOL · 2024Article
- Review
- Human immunodeficiency virus and oral microbiota: mutual influence on the establishment of a viral gingival reservoir in individuals under antiretroviral therapy.Frontiers in cellular and infection microbiology · 2024Review
- Frequency ofChildren (Basel, Switzerland) · 2022Article
- Oral Manifestations Associated with HIV/AIDS Patients.Medicina (Kaunas, Lithuania) · 2022Review
- Evaluation of Sociodemographic Factors and Prevalence of Oral Lesions in People Living with HIV from Cacoal, Rondônia, Amazon Region of Brazil.International journal of environmental research and public health · 2022Article
- Oral health status among transgender young adults: a cross-sectional study.BMC oral health · 2021Article
- The Loop-Mediated Isothermal Amplification Technique in Periodontal Diagnostics: A Systematic Review.Journal of clinical medicine · 2021Review
- Oral mycobiome identification in atopic dermatitis, leukemia, and HIV patients - a systematic review.Journal of oral microbiology · 2020Review
- A nanocarrier system that potentiates the effect of miconazole within different interkingdom biofilms.Journal of oral microbiology · 2020Article
- Association betweenCurrent medical mycology · 2020Article
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The majority of HIV-infected patients develop Candida spp-associated clinical oral lesions. Studies have shown that asymptomatic oral colonization of Candida spp may lead to oral lesions or become a source of disseminated infections. The aim of this study was to verify the effects of periodontal conditions on Candida spp prevalence and Candida spp carriage in the oral cavity of HIV-infected patients compared to non-infected patients. Twenty-five patients not infected with HIV and 48 HIV-infected patients were classified according to periodontal conditions as being periodontal healthy or with periodontal disease. Candida spp carriage and classification were performed in oral rinse samples. Viral load and CD4+ T lymphocyte (CD4+L) counts were performed in blood samples from HIV-infected patients. No differences in Candida spp prevalence related to HIV status or periodontal condition were detected. However, Candida spp carriage was increased in periodontally affected HIV-infected patients when compared to periodontally healthy HIV-infected patients (p= 0.04). Periodontally healthy HIV-infected patients presented Candida spp carriage in similar levels as healthy or periodontally affected non-HIV-infected patients. Candida spp carriage was correlated with CD4+L counting in HIV-infected patients. We concluded that periodontal disease is associated with increased Candida spp carriage in HIV-infected patients and may be a predisposing factor to clinical manifestations of candidiasis.
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