ReviewRevista do Instituto de Medicina Tropical de Sao Paulo2017
Acute kidney injury complicating bee stings - a review.
Review in Revista do Instituto de Medicina Tropical de Sao Paulo, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 75 citations in OpenAlex.
- Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom.Frontiers in immunology · 2021Trial
- Pediatric acute kidney injury following bee sting-induced anaphylaxis: a case series.Journal of medical case reports · 2026Article
- Predictors of in-hospital mortality in patients with multiple wasp stings in southwest China.Frontiers in toxicology · 2026Article
- Multisystem injury after wasp stings in the Qinling range, Shaanxi, China: clinical profile and independent predictors of poor outcome.Frontiers in medicine · 2025Article
- Diagnosis of human envenoming by terrestrial venomous animals: Routine, advances, and perspectives.Toxicon: X · 2024Article
- Article
- Relapsing nephrotic syndrome with acute renal failure following a unique episode of multiple bee stings: A case report.Clinical case reports · 2024Article
- Clinical complications in envenoming byFrontiers in immunology · 2024Review
- Multi-Organ Dysfunction Due to Envenoming Syndrome Following a Massive Bee Attack: A Fatal Case Study and Comprehensive Literature Review.International medical case reports journal · 2024Article
- Nephrotic syndrome and acute tubular injury after bee stings in a beekeeper: expanding the electron microscopic findings of bee venom-induced renal injury.International urology and nephrology · 2023Article
- The association between procalcitonin and acute kidney injury in patients stung by wasps.Frontiers in physiology · 2023Article
- Costunolide prevents renal ischemia-reperfusion injury in rats by reducing autophagy, apoptosis, inflammation, and DNA damage.Iranian journal of basic medical sciences · 2023Article
- Natural toxins and One Health: a review.Science in One Health · 2022Review
- Acute respiratory distress syndrome following multiple wasp stings treated with extracorporeal membrane oxygenation: A case report.World journal of clinical cases · 2022Article
- Wasp stings and plasma exchange.Clinical kidney journal · 2022Article
- Phenotypic and Transcriptomics Analyses Reveal Underlying Mechanisms in a Mouse Model of Corneal Bee Sting.Toxins · 2022Article
- A rare concurrence: bee venom associated acute tubular necrosis and acute interstitial nephritis.Oxford medical case reports · 2022Article
- Development and internal validation of a Wasp Sting Severity Score to assess severity and indicate blood purification in persons with Asian wasp stings.Clinical kidney journal · 2022Article
- Macroscopic hematuria in wasp sting patients: a retrospective study.Renal failure · 2021Article
- Unusual case of recurrent hypoglycaemia in multiple bee sting envenomation.BMJ case reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bee stings can cause severe reactions and have caused many victims in the last years. Allergic reactions can be triggered by a single sting and the greater the number of stings, the worse the prognosis. The poisoning effects can be systemic and can eventually cause death. The poison components are melitin, apamin, peptide 401, phospholipase A2, hyaluronidase, histamine, dopamine, and norepinephrine, with melitin being the main lethal component. Acute kidney injury (AKI) can be observed in patients suffering from bee stings and this is due to multiple factors, such as intravascular hemolysis, rhabdomyolysis, hypotension and direct toxicity of the venom components to the renal tubules. Arterial hypotension plays an important role in this type of AKI, leading to ischemic renal lesion. The most commonly identified biopsy finding in these cases is acute tubular necrosis, which can occur due to both, ischemic injury and the nephrotoxicity of venom components. Hemolysis and rhabdomyolysis reported in many cases in the literature, were demonstrated by elevated serum levels of indirect bilirubin and creatine kinase. The severity of AKI seems to be associated with the number of stings, since creatinine levels were higher, in most cases, when there were more than 1,000 stings. The aim of this study is to present an updated review of AKI associated with bee stings, including the currently advised clinical approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.