ArticlePloS one2017
Identification and characterization of CONSTANS-like (COL) gene family in upland cotton (Gossypium hirsutum L.).
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 66 citations in OpenAlex.
- Multifaceted roles of BBX transcription factors: impacts on key agronomical traits and environmental resilience.The New phytologist · 2026Review
- Genome-Wide Evolution and Stress-Responsive Regulation of 2-Oxoglutarate-Dependent Dioxygenases inGenes · 2026Article
- Genome-wide association study reveals novel SNP loci and candidate genes linked to flowering time in upland cotton.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- GhCOL2 Positively Regulates Flowering by Activating the Transcription of GhHD3A in Upland Cotton (Gossypium hirsutum L.).Biochemical genetics · 2025Article
- Transcriptome Analysis Reveals Sugar and Hormone Signaling Pathways Mediating Flower Induction in Pitaya (International journal of molecular sciences · 2025Article
- Genome-Wide Identification ofInternational journal of molecular sciences · 2025Article
- Genome-wide exploration of the CONSTANS-like (COL) gene family and its potential role in regulating plant flowering time in foxtail millet (Setaria italica).Scientific reports · 2024Article
- CONSTANS, a HUB for all seasons: How photoperiod pervades plant physiology regulatory circuits.The Plant cell · 2024Review
- The 4Fs of cotton: genome editing of cotton for fiber, food, feed, and fuel to achieve zero hunger.Frontiers in genome editing · 2024Review
- Genome-Wide Identification, Expression, and Molecular Characterization of theInternational journal of molecular sciences · 2023Article
- Diversification of plant SUPPRESSOR OF MAX2 1 (SMAX1)-like genes and genome-wide identification and characterization of cotton SMXL gene family.BMC plant biology · 2023Article
- The Current Progresses in the Genes and Networks Regulating Cotton Plant Architecture.Frontiers in plant science · 2022Review
- Genome-Wide Identification and Expression Profiling of CONSTANS-Like Genes in Pepper (Frontiers in plant science · 2022Article
- Genome-wide identification of the mangoFrontiers in plant science · 2022Article
- Roles of the 14-3-3 gene family in cotton flowering.BMC plant biology · 2021Article
- Beyond Arabidopsis: BBX Regulators in Crop Plants.International journal of molecular sciences · 2021Review
- Article
- Conservation and Divergence of theFrontiers in plant science · 2021Article
- Transcriptome profiling of the flowering transition in saffron (Crocus sativus L.).Scientific reports · 2020Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The CONSTANS/FLOWERING LOCUS T (CO/FT) regulon plays a central role in the control of flowering time in photoperiod-sensitive plants. Flowering time in wild cotton (Gossypium spp.) has strict photoperiod sensitivity, but domesticated cotton is day-neutral. Information on the molecular characterization of the CO and CO-like (COL) genes in cotton is very limited. In this study, we identified 42 COL homologs (GhCOLs) in the G. hirsutum genome, and many of them were previously unreported. We studied their chromosome distribution, phylogenetic relationships, and structures of genes and proteins. Our results showed that GhCOLs were classified into three groups, and 14 COLs in group I showed conserved structure when compared with other plants. Two homoeologous pairs, GhCOL1-A and GhCOL1-D in Group I, showed the highest sequence similarity to Arabidopsis thaliana CO and rice CO homologous gene Heading date1 (Hd1). Tissue-specific expression showed that 42 GhCOL genes may function as tissue-specific regulators in different cells or organs. We cloned and sequenced the 14 GhCOL genes in Group I related to flowering induction to study their diurnal expression pattern, and found that their expression showed distinct circadian regulation. Most of them peaked at dawn and decreased rapidly to their minima at dusk, then started to accumulate until following dawn under long- or short-day conditions. Transgenic study in the Arabidopsis co-2 mutant demonstrated that GhCOL1-A and GhCOL1-D fully rescued the late-flowering phenotype, whereas GhCOL3-A, GhCOL3-D, GhCOL7-A, and GhCOL7-D partially rescued the late-flowering phenotype, and the other five homoeologous pairs in Group I did not promote flowering. These results indicate that GhCOL1-A and GhCOL1-D were potential flowering inducers, and are candidate genes for research in flowering regulation in cotton.
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