ArticleNature biotechnology2017
Open-source, community-driven microfluidics with Metafluidics.
Article in Nature biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Article
- AI-integrated microfluidics for drug screening: From single cell to organ-on-a-chip.Acta pharmaceutica Sinica. B · 2026Review
- An open source platform to automate the design, verification, and manufacture of 3D printed microfluidic devices.Scientific reports · 2025Article
- Advancements and Prospects in DNA-Based Bioanalytical Technology for Environmental Toxicant Detection.JACS Au · 2025Review
- Designing with Printed Responsive Biomaterials: A Review.3D printing and additive manufacturing · 2025Article
- Democratizing Microreactor Technology for Accelerated Discoveries in Chemistry and Materials Research.Micromachines · 2024Review
- A Highly Sensitive Dual-Drive Microfluidic Device for Multiplexed Detection of Respiratory Virus Antigens.Micromachines · 2024Article
- Design automation of microfluidic single and double emulsion droplets with machine learning.Nature communications · 2024Article
- Open hardware: From DIY trend to global transformation in access to laboratory equipment.PLoS biology · 2023Article
- Machine learning for microfluidic design and control.Lab on a chip · 2022Review
- Gravity-Driven Microfluidic Siphons: Fluidic Characterization and Application to Quantitative Immunoassays.ACS sensors · 2021Article
- Rapid prototyping of cell culture microdevices using parylene-coated 3D prints.Lab on a chip · 2021Article
- Portable all-in-one automated microfluidic system (PAMICON) with 3D-printed chip using novel fluid control mechanism.Scientific reports · 2021Article
- Single-Cell Proteomics.Trends in biochemical sciences · 2021Review
- Conquering the Tyranny of Number With Digital Microfluidics.Frontiers in chemistry · 2021Article
- OpenWorkstation: A modular open-source technology for automatedHardwareX · 2020Article
- Open software platform for automated analysis of paper-based microfluidic devices.Scientific reports · 2020Article
- Leveraging open hardware to alleviate the burden of COVID-19 on global health systems.PLoS biology · 2020Article
- Open-source, 3D-printed Peristaltic Pumps for Small Volume Point-of-Care Liquid Handling.Scientific reports · 2020Article
- A 'poly-transfection' method for rapid, one-pot characterization and optimization of genetic systems.Nucleic acids research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Microfluidic devices have the potential to automate and miniaturize biological experiments, but open-source sharing of device designs has lagged behind sharing of other resources such as software. Synthetic biologists have used microfluidics for DNA assembly, cell-free expression, and cell culture, but a combination of expense, device complexity, and reliance on custom set-ups hampers their widespread adoption. We present Metafluidics, an open-source, community-driven repository that hosts digital design files, assembly specifications, and open-source software to enable users to build, configure, and operate a microfluidic device. We use Metafluidics to share designs and fabrication instructions for both a microfluidic ring-mixer device and a 32-channel tabletop microfluidic controller. This device and controller are applied to build genetic circuits using standard DNA assembly methods including ligation, Gateway, Gibson, and Golden Gate. Metafluidics is intended to enable a broad community of engineers, DIY enthusiasts, and other nontraditional participants with limited fabrication skills to contribute to microfluidic research.
Indexed as
Identifiers
28591125What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.