Evidence map›Paper›PMID 28591005›Full record

ArticleThe Journal of cardiovascular nursing

Implant Strategy-Specific Changes in Symptoms in Response to Left Ventricular Assist Devices.

Christopher S Lee, Jill M Gelow, Christopher V Chien, Shirin O Hiatt, Julie T Bidwell, Quin E Denfeld, Kathleen L Grady, James O Mudd

Abstract read
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In one paragraph

Article in The Journal of cardiovascular nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christopher S LeeChristopher S. Lee, PhD, RN, FAHA, FAAN, FHFSA Carol A. Lindeman Distinguished Professor, School of Nursing and Knight Cardiovascular Institute, Oregon Health & Science University, Portland. Jill M. Gelow, MD, MPH Assistant Professor, Knight Cardiovascular Institute, Oregon Health & Science University, Portland. Christopher V. Chien, MD Assistant Professor, REX Healthcare, University of North Carolina, Raleigh. Shirin O. Hiatt, MPH, MS, RN Project Coordinator, School of Nursing, Oregon Health & Science University, Portland. Julie T. Bidwell, PhD, RN Post-doctoral Fellow, Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia. Quin E. Denfeld, PhD, RN Post-doctoral Fellow, Knight Cardiovascular Institute, Oregon Health & Science University, Portland. Kathleen L. Grady, PhD, RN, FAHA, FAAN, FHFSA Professor, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. James O. Mudd, MD Associate Professor, Knight Cardiovascular Institute, Oregon Health & Science University, Portland.
Jill M Gelow
Christopher V Chien
Shirin O Hiatt
Julie T Bidwell
Quin E Denfeld
Kathleen L Grady
James O Mudd

Funding

Profiling Biobehavioral Responses to Mechanical Support in Advanced Heart FailureR01NR013492 · NINR · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEE, CHRISTOPHER SEAN · 2012 to 2015
$1.4M
NINR NIH HHS R01 NR013492
6 · The paper itself

Abstract

backgroundAlthough we know that the quality of life generally improves after left ventricular assist device (LVAD) implantation, we know little about how symptoms change in response to LVAD.

methodsThe purpose of this study was to compare the changes in symptoms between bridge and destination therapy patients as part of a prospective cohort study. Physical (dyspnea and wake disturbances) and affective symptoms (depression and anxiety) were measured before LVAD and at 1, 3, and 6 months after LVAD. Multiphase growth modeling was used to capture the 2 major phases of change: initial improvements between preimplant and 1 month after LVAD and subsequent improvements between 1 and 6 months after LVAD.

resultsThe sample included 64 bridge and 22 destination therapy patients as the preimplant strategy. Destination patients had worse preimplant dyspnea and wake disturbances, and they experienced greater initial improvements in these symptoms compared with bridge patients (all P < .05); subsequent change in both symptoms were similar between groups (both P > .05). Destination patients had worse preimplant depression (P = .042) but experienced similar initial and subsequent improvements in depression in response to LVAD compared with bridge patients (both P > .05). Destination patients had similar preimplant anxiety (P = .279) but experienced less initial and greater subsequent improvements in anxiety after LVAD compared with bridge patients (both P < .05).

conclusionThere are many differences in the magnitude and timing of change in symptom responses to LVAD between bridge and destination therapy patients. Detailed information on changes in specific symptoms may better inform shared decision-making regarding LVAD.

Indexed as

Heart-Assist DevicesAdultAgedAnxietyCohort StudiesDepressionDyspneaFemaleHeart FailureHumansMaleMiddle AgedProsthesis ImplantationQuality of LifeSleep Wake DisordersSymptom Assessment

Identifiers

PMID28591005
PMCPMC6173804

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.